Deficient autologous mixed lymphocyte reactions correlate with disease activity in systemic lupus erythematosus and rheumatoid arthritis.

JB Smith, RJ DeHoratius - Clinical and Experimental Immunology, 1982 - ncbi.nlm.nih.gov
We have examined autologous mixed lymphocyte culture (AMLC) reactions in patients with
systemic lupus erythematosus (SLE), classical rheumatoid arthritis (RA), and in normal age …

The autologous mixed lymphocyte reaction in systemic lupus erythematosus.

PJ Riccardi, PB Hausman, HV Raff… - Arthritis and …, 1982 - europepmc.org
The autologous mixed lymphocyte reaction (AMLR) represents the proliferation of T cells in
response to signals from autologous non-T cells. Fractionation of the non-T population into B …

Studies of immune functions of patients with systemic lupus erythematosus

T Sakane, AD Steinberg, FC Arnett… - … : Official Journal of …, 1979 - Wiley Online Library
In normal individuals T cells are stimulated to proliferate by autologous non‐T cells; this is
called the autologous mixed lymphocyte reaction (MLR). Previous studies demonstrated that …

Enhancement of the impaired autologous mixed leukocyte reaction in patients with systemic lupus erythematosus.

MK Crow - The Journal of clinical investigation, 1985 - Am Soc Clin Investig
The cellular basis of the impaired autologous mixed leukocyte reaction (AMLR) in patients
with systemic lupus erythematosus (SLE) was investigated. Non-T cells from normal subjects …

Suppression of the normal autologous mixed leukocyte reaction by sera from patients with systemic lupus erythematosus

BH Hahn, LS Pletscher, M Muniain… - … : Official Journal of the …, 1982 - Wiley Online Library
Sera from 15 patients with active systemic lupus erythematosus and 7 patients with inactive
lupus were added to normal autologous mixed leukocyte reaction (MLR) cultures. Twelve of …

Characterization of the defective autologous mixed lymphocyte response in rheumatoid arthritis

RM Pope, L Mcchesney, N Talal… - Arthritis & Rheumatism …, 1984 - Wiley Online Library
In order to characterize the autologous mixed lymphocyte response (AMLR) in patients with
rheumatoid arthritis (RA) and to define the relationship with disease activity, peripheral …

Responder cells in the human autologous mixed lymphocyte reaction (AMLR). Characterization and interactions in healthy individuals and patients with systemic …

JS Smolen, K Siminovitch, TA Luger… - Behring Institute …, 1983 - europepmc.org
In the course of a primary AMLR, purified T4 cells, but not purified T8 cells, proliferate to the
non-T cell stimuli; however, in the presence of T4 cells or helper factors secreted by T4 cells …

Cytotoxic responses to alloantigens in systemic lupus erythematosus

GC Tsokos, JE Balow - Journal of Clinical Immunology, 1981 - Springer
We have studied the ability of the peripheral mononuclear cells (MNC) from patients with
systemic lupus erythematosus (SLE) to generate a cytotoxic (CML) response against …

The cellular basis of the impaired autologous mixed lymphocyte reaction in patients with systemic lupus erythematosus.

MM Kuntz, JB Innes, ME Weksler - The Journal of Clinical …, 1979 - Am Soc Clin Investig
The autologous mixed lymphocyte reaction is impaired in patients with systemic lupus
erythematosus. This is because nonthymus-derived (T)-lymphocyte preparations from such …

Impaired responsiveness of lymphocytes in patients with systemic lupus erythematosus

N Suciu-Foca, JA Buda, T Thiem… - Clinical and …, 1974 - ncbi.nlm.nih.gov
Cellular immune responsiveness, as measured by lymphocyte transformation in one-way
mixed leucocyte cultures (MLC) and in phytohaemagglutinin (PHA) stimulated cultures was …