Bayesian hidden Markov modeling of array CGH data
Genomic alterations have been linked to the development and progression of cancer. The
technique of comparative genomic hybridization (CGH) yields data consisting of …
technique of comparative genomic hybridization (CGH) yields data consisting of …
Bayesian random segmentation models to identify shared copy number aberrations for array CGH data
Array-based comparative genomic hybridization (aCGH) is a high-resolution, high-
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
Hidden Markov models approach to the analysis of array CGH data
J Fridlyand, AM Snijders, D Pinkel, DG Albertson… - Journal of multivariate …, 2004 - Elsevier
The development of solid tumors is associated with acquisition of complex genetic
alterations, indicating that failures in the mechanisms that maintain the integrity of the …
alterations, indicating that failures in the mechanisms that maintain the integrity of the …
Bayesian hidden Markov modeling of array CGH data
The normal genomic code of human females consists of 23 matched pairs of chromosomes.
The genomic code of human males consists of 22 matched pairs of autosomal …
The genomic code of human males consists of 22 matched pairs of autosomal …
Continuous-index hidden Markov modelling of array CGH copy number data
Motivation: In recent years, a range of techniques for analysis and segmentation of array
comparative genomic hybridization (aCGH) data have been proposed. For array designs in …
comparative genomic hybridization (aCGH) data have been proposed. For array designs in …
A pseudolikelihood approach for simultaneous analysis of array comparative genomic hybridizations
DA Engler, G Mohapatra, DN Louis, RA Betensky - Biostatistics, 2006 - academic.oup.com
DNA sequence copy number has been shown to be associated with cancer development
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …
and progression. Array-based comparative genomic hybridization (aCGH) is a recent …
Stochastic segmentation models for array-based comparative genomic hybridization data analysis
Array-based comparative genomic hybridization (array-CGH) is a high throughput, high
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …
resolution technique for studying the genetics of cancer. Analysis of array-CGH data typically …
Analysis of array CGH data for cancer studies using fused quantile regression
Y Li, J Zhu - Bioinformatics, 2007 - academic.oup.com
Motivation: The identification of DNA copy number changes provides insights that may
advance our understanding of initiation and progression of cancer. Array-based comparative …
advance our understanding of initiation and progression of cancer. Array-based comparative …
Integrating copy number polymorphisms into array CGH analysis using a robust HMM
SP Shah, X Xuan, RJ DeLeeuw, M Khojasteh… - …, 2006 - academic.oup.com
Motivation: Array comparative genomic hybridization (aCGH) is a pervasive technique used
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
A versatile statistical analysis algorithm to detect genome copy number variation
RS Daruwala, A Rudra, H Ostrer… - Proceedings of the …, 2004 - National Acad Sciences
We have developed a versatile statistical analysis algorithm for the detection of genomic
aberrations in human cancer cell lines. The algorithm analyzes genomic data obtained from …
aberrations in human cancer cell lines. The algorithm analyzes genomic data obtained from …