Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized
clinically by cognitive decline and memory loss. The pathological features are amyloid-ß …

Alzheimer disease is a common age-related neurodegenerative disease characterized
pathologically by senile plaques, neurofibrillary tangles, synaptic disruption, and …

The amyloid β peptide is toxic to neurons, and it is believed that this toxicity plays a central
role in the progression of Alzheimer's disease. The mechanism of this toxicity is contentious …

Oxidative modifications are a hallmark of oxidative imbalance in the brains of individuals
with Alzheimer's, Parkinson's and prion diseases and their respective animal models. While …

Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder characterized
by extracellular accumulations of amyloid β (Aβ) peptides, intracellular accumulation of …

Multiple lines of evidence demonstrate that oxidative stress is an early event in Alzheimer's
disease (AD), occurring prior to cytopathology, and therefore may play a key pathogenic role …

Oxidative stress in Alzheimer's disease: Oxidative stress refers to an imbalance between the
prooxidative and anti-oxidative states that are part of normal cell metabolism that results in …

Alzheimer's disease (AD) is associated with β-amyloid accumulation, oxidative stress and
mitochondrial dysfunction. However, the effects of genetic mutation of AD on oxidative status …

Alzheimer's disease (AD) is characterized by the presence of neurofibrillary tangles, senile
plaques and loss of synapses. There is accumulating evidence that oxidative stress plays an …

Given the increasing evidence of oxidative stress in AD brain 3, 4 and studies from different
perspectives that appear to show a converging, central role for Aβ in the pathogenesis and …