Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain
R Sultana, M Perluigi, DA Butterfield - Free Radical Biology and Medicine, 2013 - Elsevier
Lipid peroxidation involves a cascade of reactions in which production of free radicals
occurs selectively in the lipid components of cellular membranes. Polyunsaturated fatty …
occurs selectively in the lipid components of cellular membranes. Polyunsaturated fatty …
[HTML][HTML] Oxidative stress in Alzheimer's disease
MA Smith, CA Rottkamp, A Nunomura, AK Raina… - … et Biophysica Acta (BBA …, 2000 - Elsevier
Oxidative balance is emerging as an important issue in understanding the pathogenesis of
Alzheimer's disease. Examination of Alzheimer's disease brain has demonstrated a great …
Alzheimer's disease. Examination of Alzheimer's disease brain has demonstrated a great …
Oxidatively modified GST and MRP1 in Alzheimer's disease brain: implications for accumulation of reactive lipid peroxidation products
R Sultana, DA Butterfield - Neurochemical research, 2004 - Springer
Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by
intracellular inclusions including neurofibrillary tangles (NFT) and senile plaques. Several …
intracellular inclusions including neurofibrillary tangles (NFT) and senile plaques. Several …
Oxidative stress and neurodegeneration: where are we now?
B Halliwell - Journal of neurochemistry, 2006 - Wiley Online Library
The brain and nervous system are prone to oxidative stress, and are inadequately equipped
with antioxidant defense systems to prevent 'ongoing'oxidative damage, let alone the extra …
with antioxidant defense systems to prevent 'ongoing'oxidative damage, let alone the extra …
Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways
Recent evidence indicates that oxidative stress occurs early in the progression of Alzheimer
disease, significantly before the development of the hallmark pathologies, namely …
disease, significantly before the development of the hallmark pathologies, namely …
Oxidative stress in Alzheimer's disease: should we keep trying antioxidant therapies?
MES Ferreira, AS de Vasconcelos… - Cellular and molecular …, 2015 - Springer
The risk of chronic diseases such as Alzheimer's disease is growing as a result of the
continuous increasing average life span of the world population, a syndrome characterized …
continuous increasing average life span of the world population, a syndrome characterized …
Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
DA Butterfield, T Reed, SF Newman… - Free Radical Biology and …, 2007 - Elsevier
Oxidative stress has been implicated to play a crucial role in the pathogenesis of a number
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease
DA Butterfield, HF Poon, DS Clair, JN Keller… - Neurobiology of …, 2006 - Elsevier
Mild cognitive impairment (MCI) is generally referred to the transitional zone between
normal cognitive function and early dementia or clinically probable Alzheimer's disease …
normal cognitive function and early dementia or clinically probable Alzheimer's disease …
Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms
R Von Bernhardi, J Eugenín - Antioxidants & redox signaling, 2012 - liebertpub.com
Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …
Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment
R Sultana, DA Butterfield - Journal of bioenergetics and biomembranes, 2009 - Springer
Alzheimer disease (AD) is an age-related neurodegenerative disorder, characterized
histopathologically by the presence of senile plaques (SP), neurofibrillary tangles and …
histopathologically by the presence of senile plaques (SP), neurofibrillary tangles and …