Aging is the major risk factor associated with neurodegenerative diseases, including
Alzheimer's disease (AD). Until now no clear understanding of the mechanisms of initiation …

Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …

Oxidative stress has been implicated in the pathogenesis of a number of diseases including
Alzheimer's disease (AD). The oxidative stress hypothesis of AD pathogenesis, in part, is …

Alzheimer's disease (AD) is characterized by progressive neurodegeneration in the cerebral
cortex, histopathologically hallmarked by amyloid β (Aβ) extracellular plaques and …

Imbalances of oxidative homeostasis and lipid peroxidation have been revealed as
important factors involved in neurodegenerative disorders such as Alzheimer's disease. The …

Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …

Alzheimer disease (AD) is a neurodegenerative disease which is characterized by the
presence of extracellular senile plaques mainly composed of amyloid-β peptide (Aβ) …

Increased awareness for a role of oxidative stress in the pathogenesis of Alzheimer's
disease has highlighted the issue of whether oxidative damage is a fundamental step in the …

Amyloid β-peptide (Aβ) is heavily deposited in the brains of Alzheimer's disease (AD)
patients, and free radical oxidative stress, particularly of neuronal lipids and proteins, is …

Oxidative stress is implicated in the pathogenesis and progression of Alzheimer's disease
(AD) and its earlier stage, amnestic mild cognitive impairment (aMCI). One source of …