Increasing numbers of individuals, particularly the elderly, suffer from neurodegenerative
disorders. These diseases are normally characterized by progressive loss of neuron cells …

A growing body of evidence suggests a relationship between oxidative stress and β‐amyloid
(Aβ) peptide accumulation, a hallmark in the pathogenesis of Alzheimer's disease (AD) …

Alzheimer disease (AD) is a neurodegenerative disease clinically characterized by
progressive cognitive dysfunction. Deposition of amyloid-β (Aβ) peptides is the most …

In Alzheimer's disease (AD), oxidative stress is present early and contributes to disease
pathogenesis. We previously reported that in Tg19959 transgenic AD mice, partial …

Astrocytes are critical for neuronal redox homeostasis providing them with cysteine needed
for glutathione synthesis. In this study, we demonstrate that the astrocytic redox response …

In Alzheimer's disease (AD) brain oxidative stress is observed indexed by several markers,
among which are protein carbonyls and 3-nitrotyrosine, markers for protein oxidation. We …

Numerous studies have shown that neuronal lipids are highly susceptible to oxidative stress
including in those brain areas directly involved in the neurodegenerative process of …

We have measured the levels of typical end products of the processes of lipid peroxidation,
protein oxidation, and total antioxidant capacity (TAC) in skin fibroblasts and lymphoblasts …

Since oxidative stress plays an important role in the pathogenesis of Alzheimer's disease
(AD) and since the age-adjusted incidence of AD is higher in females than males, we …

One of the theories involved in the etiology of Alzheimer's disease (AD) is the oxidative
stress hypothesis. The amyloid β-peptide (Aβ), a hallmark in the pathogenesis of AD and the …