Annexin 1 is an anti-inflammatory protein that plays a key role in innate immunity by
modulating the activation of several types of cells, including neutrophils. Here we have …

Annexin 1 has been shown to participate through its unique N-terminal domain in the
recruitment and activation of leukocytes at sites of inflammation. Peptides derived from this …

Annexins are characterized by the ability to bind phospholipids of membranes in the
presence of Ca2+. Annexin A5 represents a typical member of this protein family and is a …

Annexin A1 is an intracellular calcium/phospholipid-binding protein that is involved in
membrane organization and the regulation of the immune system. It has been attributed an …

Inflammation is the body's way of defending itself against noxious stimuli and pathogens.
Under normal circumstances, the body is able to eliminate the insult and subsequently …

The engulfment of apoptotic cells is of crucial importance for tissue homeostasis in
multicellular organisms. A failure of this process results in secondary necrosis triggering …

Human polymorphonuclear leukocytes adhesion to endothelial cells during the early stage
of inflammation leads to cell surface externalization of Annexin A1 (AnxA1), an effector of …

A hallmark of inflammation is the mobilization of blood-borne leukocytes across
microvessels to kill and remove the invading pathogen. For its damaging potential, leukocyte …

Neutrophils (also named polymorphonuclear leukocytes or PMN) are essential components
of the immune system, rapidly recruited to sites of inflammation, providing the first line of …

According to Aristotle,“The whole is greater than the sum of its parts” and yet, although a
long time has passed still, we seem to struggle to accept this universal concept. Searching in …