Annexin A1 is a protein with multifunctional roles in innate and adaptive immunity mainly
devoted to the regulation of inflammatory cells and the resolution of inflammation. Most of …

Abstract Annexin 3 (ANX A3) represents∼ 1% of the total protein of human neutrophils and
promotes tight contact between membranes of isolated specific granules in vitro leading to …

Abstract Annexin 1 (ANXA1) is the first characterized member of the annexin family of
proteins able to bind (ie to annex) to cellular membranes in a calcium-dependent manner …

Annexin-1 is an anti-inflammatory protein that plays an important homeostatic role in innate
immunity; however, its potential actions in the modulation of adaptive immunity have never …

Annexin 2 is a profibrinolytic co-receptor for plasminogen and tissue plasminogen activator
that stimulates activation of the major fibrinolysin, plasmin, at cell surfaces. In human …

On the surface of the macrophage, annexin A2 tetramer (A2t) serves as a docking protein or
recognition element for bacterial and viral pathogens. Plasma levels of free A2t have been …

Engulfment of apoptotic cells requires presentation of new cell surface ligands by the dying
cells. Using a differential proteomics technology, we identify that annexin I is a caspase …

The resolution of inflammation is a dynamically regulated process that may be subverted in
many pathological conditions. Macrophage (Mφ) phagocytic clearance of apoptotic …

Annexin A2 has been implicated in several immune modulated diseases including
Rheumatoid arthritis (RA) pannus formation. The most relied treatment option for RA …

The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and
phospholipid binding protein family which share a high structural homology. In keeping with …