Background The ability to deliver a gene of interest into a specific cell type is an essential
aspect of biomedical research. Viruses can be a useful tool for this delivery, particularly in …

Adeno-associated virus (AAV) vectors have made great progress in their use for gene
therapy; however, fundamental aspects of AAV's capsid assembly remain poorly …

In recent years recombinant adeno-associated viral vectors (AAV) have become
increasingly valuable for in vivo studies in animals, and are also currently being tested in …

Infection with wild-type adeno-associated virus (AAV) is common in humans, but very little is
known about the in vivo biology of AAV. On a molecular level, it has been shown in cultured …

Adeno-associated virus (AAV) vectors are extremely effective gene-delivery vehicles for a
broad range of applications. However, the therapeutic efficacy of these and other vectors is …

Abstract The Adeno-associated viruses (AAVs) are not associated with any diseases, and
their ability to package non-genomic DNA and to transduce different cell/tissue populations …

Recombinant adeno-associated viruses (AAVs) have unique gene-transfer properties that
speak to their potential as carriers for gene therapy or vaccine applications. However, the …

Vectors based on different serotypes of adeno-associated virus hold great promise for
human gene therapy, based on their unique tissue tropisms and distinct immunological …

Adeno-associated virus (AAV) replication depends on two viral components for replication:
the AAV nonstructural proteins (Rep) in trans, and inverted terminal repeat (ITR) sequences …

Adeno-associated virus (AAV) is a prevalent human virus whose replication requires factors
provided by a coinfecting helper virus. AAV can establish latent infections in vitro by …