Reactive oxygen species (ROS), a heterogeneous population of biologically active
intermediates, are generated as by-products of the aerobic metabolism and exhibit a dual …

Under physiological conditions, intracellular and tissue levels of reactive oxygen species
(ROS) are carefully controlled and employed as fine modulators of signal transduction, gene …

Reactive oxygen species (ROS) generated within cells or, more generally, in a tissue
environment, may easily turn into a source of cell and tissue injury. Aerobic organisms have …

Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging
from metabolic to proliferative ones, and is a major cause of liver damage due to …

Reactive oxygen species-(ROS-) induced oxidative stress has been implicated in various
forms of diseases. Excessive ROS generation depletes the endogenous antioxidants that …

Liver diseases are a worldwide medical problem because the liver is the principal
detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various …

Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

The increased production of derivatives of molecular oxygen and nitrogen in the form of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) lead to molecular …

Oxidative stress is a common pathogenetic mechanism contributing to initiation and
progression of hepatic damage in a variety of liver disorders. Cell damage occurs when …

The importance of a correct balance between oxidative and reductive events has been
shown to have a paramount effect on cell function for quite a long time. However, in spite of …