Metastatic heterogeneity of breast cancer: Molecular mechanism and potential therapeutic targets

Y Liang, H Zhang, X Song, Q Yang - Seminars in cancer biology, 2020 - Elsevier
Breast cancer is one of the most common malignancies among women throughout the world
and is the major cause of most cancer-related deaths. Several explanations account for the …

[HTML][HTML] Clinical and molecular complexity of breast cancer metastases

S Kimbung, N Loman, I Hedenfalk - Seminars in cancer biology, 2015 - Elsevier
Clinical oncology is advancing toward a more personalized treatment orientation, making
the need to understand the biology of metastasis increasingly acute. Dissecting the complex …

Breast cancer metastasis: mechanisms and therapeutic implications

M Park, D Kim, S Ko, A Kim, K Mo, H Yoon - International journal of …, 2022 - mdpi.com
Breast cancer is the most common malignancy in women worldwide. Metastasis is the
leading cause of high mortality in most cancers. Although predicting the early stage of breast …

Targeting breast cancer metastasis

X Jin, P Mu - Breast cancer: basic and clinical research, 2015 - journals.sagepub.com
Metastasis is the leading cause of breast cancer-associated deaths. Despite the significant
improvement in current therapies in extending patient life, 30–40% of patients may …

Breast cancer metastasis

MY Kim - Translational Research in Breast Cancer, 2021 - Springer
Owing to increased awareness of the importance of mammogram and advances in surgical
technology, survival rate of patients with primary breast cancer has dramatically increased …

Breast cancer metastasis

OJ Scully, BH Bay, G Yip, Y Yu - Cancer genomics & proteomics, 2012 - cgp.iiarjournals.org
Breast cancer metastasis accounts for the majority of deaths from breast cancer. Detection of
breast cancer metastasis at the earliest stage is important for the management and …

Emerging therapeutic targets in metastatic progression: a focus on breast cancer

Z Li, Y Kang - Pharmacology & therapeutics, 2016 - Elsevier
Metastasis is the underlying cause of death for the majority of breast cancer patients.
Despite significant advances in recent years in basic research and clinical development …

Molecular mechanisms of breast cancer metastasis to the lung: clinical and experimental perspectives

B Medeiros, AL Allan - International journal of molecular sciences, 2019 - mdpi.com
Breast cancer is the most commonly diagnosed cancer in women worldwide, and> 90% of
breast cancer-related deaths are associated with metastasis. Breast cancer spreads …

Mechanisms of breast cancer metastasis

SD Nathanson, M Detmar, TP Padera, LR Yates… - Clinical & experimental …, 2022 - Springer
Invasive breast cancer tends to metastasize to lymph nodes and systemic sites. The
management of metastasis has evolved by focusing on controlling the growth of the disease …

[HTML][HTML] Breast cancer metastasis: issues for the personalization of its prevention and treatment

N Marino, S Woditschka, LT Reed, J Nakayama… - The American journal of …, 2013 - Elsevier
Despite important progress in adjuvant and neoadjuvant therapies, metastatic disease often
develops in breast cancer patients and remains the leading cause of their deaths. For …