Extracellular levels of dopamine are increased in response to systemic administration of
cocaine in several brain areas including the nucleus accumbens and medial prefrontal …

J. Neurochem.(2011) 119, 332–341. Abstract Repeated exposure to cocaine progressively
increases drug‐induced locomotor activity, which is termed behavioral sensitization …

It has been postulated that behavioral sensitization to cocaine is associated with an
attenuation of cocaine-induced dopamine (DA) transmission in the medial prefrontal cortex …

Repeated administration of cocaine progressively increases drug-induced locomotor
activity. This study examined the role of dopamine D1-and D2-like receptors in the medial …

Rats were treated chronically with 20 mg/kg/day cocaine (by intraperitoneal injection) for 16
days, followed by 7 days of cocaine wash-out. On the next day, rats were challenged with an …

The medial prefrontal cortex (mPFC) has been implicated in the development of behavioral
sensitization, which is the progressive enhancement of locomotor activity that occurs with …

The effects of neurotoxic lesions to the medial prefrontal cortex on both the acquisition and
maintenance of intravenous cocaine self-administration were examined. In one experiment …

Data from the authors' laboratory on the neural substrates of Pavlovian conditioning and
behavioral sensitization to psychomotor stimulants are reviewed. The findings of a recent …

In the present work, we assessed dopamine extracellular levels in the medial Prefrontal
Cortex of rats repeatedly treated with amphetamine during early abstinence. Rats were …

Rationale Recent studies have suggested that the medial prefrontal cortex (mPFC) plays an
important role in the development of sensitization to cocaine. In particular, a recent report …