Malaria during the first pregnancy causes a high rate of fetal and neonatal death. The
decreasing susceptibility during subsequent pregnancies correlates with acquisition of …

Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium
falciparum in the placenta, but the parasite ligand involved in adhesion has not previously …

Plasmodium falciparum parasites express variant adhesion molecules on the surface of
infected erythrocytes (IEs), which act as targets for natural protection. Recently it was shown …

In high‐transmission regions, protective clinical immunity to Plasmodium falciparum
develops during the early years of life, limiting serious complications of malaria in young …

Plasmodium falciparum–infected erythrocytes bind to chondroitin sulfate A (CSA) in the
placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane …

In areas where Plasmodium falciparum is endemic, pregnant women are at increased risk
for malaria, and this risk is greatest during the first pregnancy. The placenta sequesters …

Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-
infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated …

Malaria during pregnancy causes serious disease that is associated with sequestration in
the placenta of Plasmodium falciparum infected erythrocytes that adhere to several host …

Placental malaria, caused by sequestration of Plasmodium falciparum-infected erythrocytes
in the placenta, is associated with increased risk of maternal morbidity and poor birth …

The harmful effects of pregnancy-associated malaria (PAM) are engendered by the heavy
sequestration of Plasmodium falciparum-parasitized RBCs in the placenta. It is well …