Elevated levels of inflammation markers predict poor outcomes in acute ischemic stroke patients after intravenous thrombolysis

D Hu, C Ding, X Jiang, J Xiao, C Li, L Zhang, T Li… - Journal of Stroke and …, 2021 - Elsevier
Objectives Inflammation is associated with the occurrence and prognosis of ischemic stroke.
The aim of this study was to evaluate the association between inflammatory biomarkers and …

[HTML][HTML] Prognostic significance of plasma IL-2 and sIL-2Rα in patients with first-ever ischaemic stroke

H Zhao, F Li, Y Huang, S Zhang, L Li, Z Yang… - Journal of …, 2020 - Springer
Background An imbalance between circulating neuroprotective and neurotoxic T cell
subsets leads to poor prognosis in acute ischaemic stroke (AIS). Preclinical studies have …

Systemic inflammation in hemorrhagic strokes–A novel neurological sign and therapeutic target?

AR Saand, F Yu, J Chen… - Journal of Cerebral Blood …, 2019 - journals.sagepub.com
Growing evidences suggest that stroke is a systemic disease affecting many organ systems
beyond the brain. Stroke-related systemic inflammatory response and immune …

[HTML][HTML] Interleukin-11 treatment protected against cerebral ischemia/reperfusion injury

B Zhang, HX Zhang, ST Shi, YL Bai, X Zhe… - Biomedicine & …, 2019 - Elsevier
Objective Inflammation and immune responses are crucial factors associated with the onset
and progression of stroke. Interleukin-11 (IL-11) is a hematopoietic IL-6 family cytokine that …

[HTML][HTML] Neuroinflammatory biomarkers: from stroke diagnosis and prognosis to therapy

A Simats, T García-Berrocoso, J Montaner - Biochimica et Biophysica Acta …, 2016 - Elsevier
Stroke is the third leading cause of death in industrialized countries and one of the largest
causes of permanent disability worldwide. Therapeutic options to fight stroke are still limited …

Circulating immune cell landscape in patients who had mild ischaemic stroke

YE Cho, H Lee, HR Bae, H Kim, S Yun… - Stroke and vascular …, 2022 - svn.bmj.com
Introduction Patients who had a mild ischaemic stroke who present with subtle or resolving
symptoms sometimes go undiagnosed, are excluded from treatment and in some cases …

[HTML][HTML] Integrated analysis of the proteome and transcriptome in a MCAO mouse model revealed the molecular landscape during stroke progression

L Li, L Dong, Z Xiao, W He, J Zhao, H Pan… - Journal of Advanced …, 2020 - Elsevier
Strokes usually results in long-term disability and death, and they occur worldwide.
Recently, increased research on both on the physiopathological mechanisms and the …

[HTML][HTML] Association of clinical and aetiologic subtype of acute ischaemic stroke with inflammation, oxidative stress and vascular function: a cross-sectional …

C Beer, D Blacker, GJ Hankey… - Medical science monitor …, 2011 - ncbi.nlm.nih.gov
Background The role of inflammation, vascular dysfunction and oxidative stress in the
pathophysiology of different stroke subtypes is not well understood. We aimed to determine …

[HTML][HTML] Prognostic role of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune inflammation index in acute ischemic stroke: a STROBE …

LH Li, CT Chen, YC Chang, YJ Chen, IH Lee, CK How - Medicine, 2021 - journals.lww.com
The acute ischemic stroke (AIS) is a devastating disease and remains the leading cause of
death and disability. This study aims to evaluate the role of hematological inflammatory …

[HTML][HTML] Blood/brain biomarkers of inflammation after stroke and their association with outcome: from C-reactive protein to damage-associated molecular patterns

A Bustamante, A Simats, A Vilar-Bergua… - …, 2016 - Elsevier
Stroke represents one of the most important causes of disability and death in developed
countries. However, there is a lack of prognostic tools in clinical practice to monitor the …