[HTML][HTML] Luteolin, a bioflavonoid inhibits azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2

AK Pandurangan, SAS Kumar… - Pharmacognosy …, 2014 - ncbi.nlm.nih.gov
Colon cancer (CRC) is a serious health problem through worldwide. Development of novel
drug without side effect for this cancer was crucial. Luteolin (LUT), a bioflavonoid has many …

Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/β-catenin pathway

P Ashokkumar, G Sudhandiran - Investigational new drugs, 2011 - Springer
The protective role of Luteolin (LUT) against Azoxymethane (AOM)-induced mouse colon
carcinogenesis has been documented earlier. The aim of this study is to investigate on the …

Luteolin, a bioflavonoid inhibits Azoxymethane-induced colorectal cancer through activation of Nrf2 signaling

AK Pandurangan, SK Ananda Sadagopan… - Toxicology …, 2014 - Taylor & Francis
Colorectal cancer (CRC) is now perceived as a multistep process characterized by the
accumulation of genetic alterations in oncogenes and tumor suppressor genes. Plant …

Protective role of luteolin on the status of lipid peroxidation and antioxidant defense against azoxymethane-induced experimental colon carcinogenesis

P Ashokkumar, G Sudhandiran - Biomedicine & Pharmacotherapy, 2008 - Elsevier
The modifying effect of dietary exposure to a flavonoid, luteolin (LUT) during the
azoxymethane (AOM)-induced colon carcinogenesis was investigated in this study. Aberrant …

Luteolin inhibits matrix metalloproteinase 9 and 2 in azoxymethane-induced colon carcinogenesis

AK Pandurangan, P Dharmalingam… - Human & …, 2014 - journals.sagepub.com
The present investigation deals with the antimetastatic role of luteolin (LUT) by inhibiting
matrix metalloproteinase (MMP)-9 and-2 in azoxymethane (AOM)-induced colon …

Effect of luteolin on the levels of glycoproteins during azoxymethane-induced colon carcinogenesis in mice

AK Pandurangan, P Dharmalingam… - Asian Pacific journal …, 2012 - koreascience.kr
Luteolin (LUT), a bioflavonoid has been used as a chemopreventive agent world-wide
against chemically induced cancer. Hence we designed an experiment to assess …

Luteolin, a bioflavonoid, attenuates azoxymethane-induced effects on mitochondrial enzymes in BALB/c mice

AK Pandurangan, SKA Sadagopan… - Asian Pacific Journal …, 2013 - journal.waocp.org
Colon cancer (CRC) is a serious health problem throughout the world. Development of
novel drugs without sideeffects for this cancer is crucial. Luteolin (LUT), a bioflavonoid, has …

Lawsone suppresses azoxymethane mediated colon cancer in rats and reduces proliferation of DLD-1 cells via NF-κB pathway

SB Wang, Z Tao, P Li - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Lawsone (LS) a colored napthoquinone compound obtained from the plant Lawsonia
inermis L.(Lythraceae) is known for its usefulness of being a precursor for synthesis of some …

Luteolin supplementation adjacent to aspirin treatment reduced dimethylhydrazine-induced experimental colon carcinogenesis in rats

NHA Osman, UZ Said, AM El-Waseef, ESA Ahmed - Tumor Biology, 2015 - Springer
Previous studies have shown that aspirin is used in colon cancer treatment. However, long-
term of Aspirin usage is limited to gastric and renal toxicity. Luteolin (LUT) has cancer …

Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF‐κB, iNOS, COX‐2, TNF‐α, and IL‐6 in 1, 2‐dimethylhydrazine‐induced rat …

S Umesalma, G Sudhandiran - Basic & clinical pharmacology & …, 2010 - Wiley Online Library
Dietary polyphenols have been found to possess preventive and therapeutic potential
against several types of cancers. We investigated the effect of ellagic acid on colon cancer …