Genetic predisposition plays a crucial role in susceptibility to systemic lupus erythematosus
(SLE) in both human patients and animal models. Recent progress in experimental systems …

Systemic lupus erythematosus (SLE; OMIM 152700) is a highly heterogeneous disorder,
characterized by differences in autoantibody profile, serum cytokines, and a multi-system …

Systemic lupus erythematosus (SLE) is a multisystemic, autoimmune disease,
encompassing either mild or severe manifestations. SLE was originally labeled as being an …

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease with
partially understood etiology, which can affect virtually any organ. Despite suggestions to the …

We are currently witnessing an explosion of information about the genetic contribution to
complex human diseases such as systemic lupus erythematosus (SLE). These genetic …

Cutaneous features of the protean disease lupus erythematous (LE) constitute 4 of 11
diagnostic criteria for systemic lupus erythematosus (SLE) and are exhibited by …

Systemic lupus erythematosus (SLE) is a complex polygenic autoimmune disease
characterized by the presence of anti‐nuclear autoantibodies (ANAs) that are often …

Disease heterogeneity remains a major challenge for the understanding of systemic lupus
erythematosus (SLE). Recent work has revealed the important role of nonimmune factors in …

Systemic lupus erythematosus (SLE) is characterized by the dysfunction of T cells, B cells,
and dendritic cells, the release of pro-inflammatory nuclear materials from necrotic cells, and …

The underlying trigger for systemic lupus erythematosus (SLE) has remained elusive, and
multiple interacting environmental and genetic factors likely contribute to the onset and …