Background: Congenital heart disease (CHD) constitutes the most prevalent and
heterogeneous group of congenital anomalies. Although surgery remains the gold standard …

Congenital heart disease (CHD) is the most prevalent congenital anomaly in newborn
babies. Cardiac malformations have been induced in different animal model experiments, by …

Dramatic evolution in medical and catheter interventions and complex surgeries to treat
children with congenital heart disease (CHD) has led to a growing number of patients with a …

Hypoplastic left heart syndrome is a type of congenital heart disease characterized by
underdevelopment of the left ventricle, outflow tract, and aorta. The condition is fatal if …

Cell therapies specifically targeting heart failure could greatly decrease morbidity and
burgeoning health care costs worldwide. Due to the great number of cell types being …

This review article reports on the new field of stem cell therapy and tissue engineering and
its potential on the management of congenital heart disease. To date, stem cell therapy has …

Single ventricle physiology, especially hypoplastic left heart syndrome, is one of the most
high-risk lesions in children with congenital heart disease, and the ensuing heart failure …

CD45− mononuclear cells obtained from myocardial biopsies. The CArdiosphere-Derived
aUtologous stem cElls to reverse ventricUlar dySfunction (CADUCEUS) trial was a …

Objective Despite the increasing incidence of right ventricular (RV) failure in adult patients
with congenital heart disease, current therapeutic options are still limited. By contrast to left …

Heart failure is a leading cause of death worldwide. Current therapies only delay
progression of the cardiac disease or replace the diseased heart with cardiac …