Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds

R Sinha, K El-Bayoumy - Current cancer drug targets, 2004 - ingentaconnect.com
Epidemiological studies, preclinical investigations and clinical intervention trials support the
role of selenium compounds as potent cancer chemopreventive agents; the dose and the …

Selenium compounds and apoptotic modulation: a new perspective in cancer therapy

C Sanmartin, D Plano, JA Palop - Mini reviews in medicinal …, 2008 - ingentaconnect.com
Recent epidemiological studies have demonstrated that selenium may be an effective
chemopreventive and anticancer agent with a broad spectrum against several human …

Molecular targets for selenium in cancer prevention

YS Kim, J Milner - Selenium and Cancer, 2001 - taylorfrancis.com
Mounting evidence reveals that selenium is a dietary constituent with anticarcinogenic and
antitumorigenic properties. Various forms of selenium appear to be effective in bringing …

Apoptotic cellular events for selenium compounds involved in cancer prevention

H Rikiishi - Journal of bioenergetics and biomembranes, 2007 - Springer
Converging data from epidemiological, ecological, and clinical studies have shown that
selenium (Se) can decrease the risk for some types of human cancers. Induction of …

Selenium cytotoxicity in cancer

M Wallenberg, S Misra… - Basic & clinical …, 2014 - Wiley Online Library
Selenium is an essential trace element with growth‐modulating properties. Decades of
research clearly demonstrate that selenium compounds inhibit the growth of malignant cells …

[HTML][HTML] Selenium as an essential micronutrient: roles in cell cycle and apoptosis

H Zeng - Molecules, 2009 - mdpi.com
Selenium is an essential trace element for humans and animals, and selenium deficiency is
associated with several disease conditions such as immune impairment. In addition …

Enhanced sensitivity of human oral carcinomas to induction of apoptosis by selenium compounds: involvement of mitogen-activated protein kinase and Fas pathways

A Ghose, J Fleming, K El-Bayoumy, PR Harrison - Cancer research, 2001 - AACR
Prospective studies and recent intervention trials suggest that the risk of some cancers,
including respiratory tract cancers, may be inversely related to selenium (SE) intake, and this …

New concepts in selenium chemoprevention

C Ip, Y Dong, HE Ganther - Cancer and Metastasis Reviews, 2002 - Springer
This article highlights some recent advances in selenium cancer chemoprevention research.
It has been well documented that the chemical transformation of selenium to a …

Distinct Effects of Methylseleninic Acid versus Selenite on Apoptosis, Cell Cycle, and Protein Kinase Pathways in DU145 Human Prostate Cancer Cells

C Jiang, Z Wang, H Ganther, J Lu - Molecular cancer therapeutics, 2002 - AACR
Selenium has been implicated as a promising chemopreventive agent for prostate cancer.
Whereas the anticancer mechanisms have not been clearly defined, one hypothesis relates …

Organoselenium compounds in cancer chemoprevention

R Naithani - Mini reviews in medicinal chemistry, 2008 - ingentaconnect.com
Selenium is an important trace element involved in different physiological functions of
human body. Knowledge of selenium in biology of cancer has increased at rapid rate …