Abstract A phase I/II study evaluated the pharmacokinetics, tolerability, and antiviral activity
of oral ganciclovir in persons infected with human immunodeficiency virus (HIV). Oral …

Ganciclovir is a nucleoside analog which inhibits the replication of herpesviruses in vitro and
which has been effective by intravenous administration for the treatment of severe …

Oral ganciclovir has recently been approved for use in long-term maintenance therapy in the
treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients. Although oral …

Objective Ganciclovir is commonly used in the treatment of cytomegalovirus (CMV) disease
in patients who are immunocompromised and for the prevention of CMV disease in solid …

Objective To investigate whether low ganciclovir serum levels in patients on maintenance
oral ganciclovir therapy are associated with recurrence of CMV retinitis. Methods A …

The pharmacokinetics, safety, tolerance, and antiviral effects of ganciclovir (Gcv)
administered orally were evaluated in 36 children infected with cytomegalovirus (CMV) who …

As a result of the low oral bioavailability of ganciclovir, a prodrug was developed to improve
the bioavailability of ganciclovir. This study was designed to investigate the fasting, single …

Plasma concentration of ganciclovir was studied prospectively in 15 AIDS patients treated
for acute cytomegalovirus (CMV) retinitis. Ganciclovir was administered at a mean dose of …

Valganciclovir, an oral prodrug of the anti-cytomegalovirus (CMV) agent ganciclovir, was
evaluated in a single-arm open-label safety study. AIDS patients (median CD4 lymphocyte …

Valganciclovir (Valcyte™) is an orally administered prodrug of the standard anti-
cytomegalovirus (CMV) drug ganciclovir. Valganciclovir is as effective as intravenous …