[HTML][HTML] Immunomodulation by helminths: intracellular pathways and extracellular vesicles

A Zakeri, EP Hansen, SD Andersen… - Frontiers in …, 2018 - frontiersin.org
Helminth parasites are masters at manipulating host immune responses, using an array of
sophisticated mechanisms. One of the major mechanisms enabling helminths to establish …

[HTML][HTML] Helminth parasites and immune regulation

PH Gazzinelli-Guimaraes, TB Nutman - F1000Research, 2018 - ncbi.nlm.nih.gov
Helminth parasites are complex metazoans that belong to different taxonomic families but
that collectively share the capacity to downregulate the host immune response directed …

[HTML][HTML] Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity

JP Hewitson, JR Grainger, RM Maizels - Molecular and biochemical …, 2009 - Elsevier
Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …

[HTML][HTML] Regulation of the host immune system by helminth parasites

RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Modulation of specific and allergy‐related immune responses by helminths

E Daniłowicz-Luebert, NL O′ Regan… - BioMed Research …, 2011 - Wiley Online Library
Helminths are master regulators of host immune responses utilising complex mechanisms to
dampen host protective Th2‐type responses and favour long‐term persistence. Such …

Helminth parasites–masters of regulation

RM Maizels, A Balic, N Gomez‐Escobar… - Immunological …, 2004 - Wiley Online Library
Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

[HTML][HTML] Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules

RM Maizels, HH Smits, HJ McSorley - Immunity, 2018 - cell.com
Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …

Immunomodulation by helminth parasites: defining mechanisms and mediators

HJ McSorley, JP Hewitson, RM Maizels - International journal for …, 2013 - Elsevier
Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …

[HTML][HTML] Harnessing helminth-driven immunoregulation in the search for novel therapeutic modalities

SM Ryan, RM Eichenberger, R Ruscher… - PLoS …, 2020 - journals.plos.org
Parasitic helminths have coevolved with humans over millennia, intricately refining and
developing an array of mechanisms to suppress or skew the host's immune system, thereby …

On the hunt for helminths: innate immune cells in the recognition and response to helminth parasites

JG Perrigoue, FA Marshall, D Artis - Cellular microbiology, 2008 - Wiley Online Library
The generation of protective immunity to helminth parasites is critically dependent upon the
development of a CD4+ T helper type 2 cytokine response. However, the host–parasite …