[HTML][HTML] Clostridioides difficile infection: are the three currently used antibiotic treatment options equal from pharmacological and microbiological points of view?

M Krutova, M Wilcox, E Kuijper - International Journal of Infectious Diseases, 2022 - Elsevier
Recently, the recommendations for the treatment of Clostridioides difficile infection (CDI)
have been updated. However, in addition to the clinical efficacy data, the drug of choice …

Advances in Therapeutic Strategies for the Management of Clostridioides difficile Infection

A Vitiello, M Sabbatucci, A Zovi, A Salzano… - Journal of Clinical …, 2024 - mdpi.com
The infection caused by Clostridioides difficile represents one of the bacterial infections with
the greatest increase in incidence among nosocomial infections in recent years. C. difficile is …

[HTML][HTML] The management of Clostridioides difficile infection: from empirism to evidence

IŞ Deac, AM Ofrim, RA Fărcaş, S Grad… - Medicine and …, 2024 - ncbi.nlm.nih.gov
Clostridioides difficile infection (CDI) in clinical practice represents a challenge for its
management and also prevention of recurrence. Even though there are updated guidelines …

Clostridioides difficile infections; new treatments and future perspectives

C Normington, CH Chilton… - Current Opinion in …, 2024 - journals.lww.com
With current first-in-line antibiotic therapy options associated with high levels of recurrent
CDI, the availability of new generation targeted therapeutics can really impact treatment …

[HTML][HTML] Fidaxomicin versus metronidazole, vancomycin and their combination for initial episode, first recurrence and severe Clostridioides difficile infection—an …

S Polivkova, M Krutova, V Capek, B Sykorova… - International Journal of …, 2021 - Elsevier
Purpose We aimed to evaluate the efficacy of different antibiotic regimens for the treatment
of Clostridioides difficile infection (CDI) with regard to the CDI episode number and disease …

[HTML][HTML] Frontiers in antibiotic alternatives for Clostridioides difficile infection

M Phanchana, P Harnvoravongchai… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Clostridioides difficile (C. difficile) is a gram-positive, anaerobic spore-forming bacterium and
a major cause of antibiotic-associated diarrhea. Humans are naturally resistant to C. difficile …

Management of Clostridioides difficile colitis: insights for the gastroenterologist

S Saha, S Khanna - Therapeutic Advances in …, 2019 - journals.sagepub.com
Clostridioides difficile infection (CDI) is a common cause of diarrhea in both inpatient and
outpatient settings. The last few years have seen major changes in the treatment spectrum of …

Clostridioides difficile infection (CDI): A pan-European multi-center cost and resource utilization study, results from the Combatting Bacterial Resistance in Europe CDI …

SM Wingen-Heimann, K Davies, VF Viprey… - Clinical Microbiology …, 2023 - Elsevier
Objectives Clostridioides difficile infection (CDI) is one of the leading nosocomial infections
worldwide, resulting in a significantly increasing burden on the healthcare systems …

Antibiotic Treatment Pipeline for Clostridioides difficile Infection (CDI): A Wide Array of Narrow-Spectrum Agents

TJ Carlson, AJ Gonzales-Luna - Current Infectious Disease Reports, 2020 - Springer
Abstract Purpose of Review Clostridioides difficile infection (CDI) represents a major burden
on the US healthcare system. Despite the US Food and Drug Administration (FDA) approval …

Clostridioides difficile infection: update on management

A Mounsey, KL Smith, VC Reddy, S Nickolich - American family physician, 2020 - aafp.org
Guidelines for the diagnosis and treatment of Clostridioides difficile infection have recently
been updated. Risk factors include recent exposure to health care facilities or antibiotics …