[HTML][HTML] Emerging immunomodulatory strategies for cell therapeutics

CYX Chua, AY Jiang, T Eufrásio-da-Silva… - Trends in …, 2023 - cell.com
Cellular therapies are poised to transform the field of medicine by restoring dysfunctional
tissues and treating various diseases in a dynamic manner not achievable by conventional …

The emerging landscape of immune cell therapies

EW Weber, MV Maus, CL Mackall - Cell, 2020 - cell.com
Cell therapies present an entirely new paradigm in drug development. Within this class,
immune cell therapies are among the most advanced, having already demonstrated …

Prospects of the use of cell therapy to induce immune tolerance

Z Wang, X Liu, F Cao, JA Bellanti, J Zhou… - Frontiers in …, 2020 - frontiersin.org
Conditions in which abnormal or excessive immune responses exist, such as autoimmune
diseases (ADs), graft-versus-host disease, transplant rejection, and hypersensitivity …

Translation of cell therapies to treat autoimmune disorders

JM Mehta, SC Hiremath, C Chilimba, A Ghasemi… - Advanced Drug Delivery …, 2023 - Elsevier
Autoimmune diseases are a diverse and complex set of chronic disorders with a substantial
impact on patient quality of life and a significant global healthcare burden. Current …

Immunological considerations and challenges for regenerative cellular therapies

S Petrus-Reurer, M Romano, S Howlett… - Communications …, 2021 - nature.com
The central goal of regenerative medicine is to replace damaged or diseased tissue with
cells that integrate and function optimally. The capacity of pluripotent stem cells to produce …

Cell therapies in the clinic

LLW Wang, ME Janes, N Kumbhojkar… - Bioengineering & …, 2021 - Wiley Online Library
Cell therapies have emerged as a promising therapeutic modality with the potential to treat
and even cure a diverse array of diseases. Cell therapies offer unique clinical and …

The cellular immunotherapy revolution: arming the immune system for precision therapy

RD Paucek, D Baltimore, G Li - Trends in immunology, 2019 - cell.com
Immunotherapy treatments harnessing the patient's immune system herald a new era of
personalized medicine, offering hope for curative responses in patients with serious …

Cell therapy: types, regulation, and clinical benefits

AEH El-Kadiry, M Rafei, R Shammaa - Frontiers in Medicine, 2021 - frontiersin.org
Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Modulation of the activity of stem and progenitor cells by immune cells

YK Alshoubaki, B Nayer, S Das… - Stem Cells …, 2022 - academic.oup.com
Numerous components of the immune system, including inflammatory mediators, immune
cells and cytokines, have a profound modulatory effect on the homeostatic regulation and …

Personalizing stem cell research and therapy: the arduous road ahead or missed opportunity?

SA Patel, CC King, PK Lim, U Habiba… - Current …, 2010 - ingentaconnect.com
The euphoria of stem cell therapy has diminished, allowing scientists, clinicians and the
general public to seriously re-examine how and what types of stem cells would effectively …