Serial electrocardiograms and serum digoxin levels were obtained in four healthy volunteers
receiving daily doses of digoxin, 0.25 mg for the first two weeks and 0.5 mg for two more …

The relation between serum digoxin concentration and the electrocardiogram was assessed
by correlating computerized measurements of electrocardiographic parameters (PR, QRS …

In 48 patients a significantly elevated plasma digoxin concentration (2.5 micrograms/l or
more) correlated with the clinical symptoms and the electrocardiogram. The rhythm and …

Factors influencing serum digoxin concentrations, and the relation of these levels to
classical electrocardiographic (ECG) and clinical manifestations of toxicity, were assessed in …

The criteria which a drug must fulfil before it can be said that it may be worthwhile making
regular plasma concentration measurements of that drug in monitoring therapy are …

The effect of incremental diltiazem dosing during concomitant digoxin administration over a
four-week period in eight healthy adult volunteers (mean age, 28±4 years) was studied. The …

Although the role of digoxin therapy has been the subject of debate, the drug is generally
accepted as effective in the treatment of heart failure due to systolic dysfunction and as …

Ten digitalized patients were monitored for detection of cardiac arrhythmias 0 to 8 hr after
daily maintenance dose of digoxin in the fasting state. Transient cardiac arrhythmias …

Four elderly female patients in sinus rhythm and with mild congestive cardiac failure were
treated with digoxin and studied over a 6‐month period. There were significant linear …

A dose-response relation between cardiac glycosides and systolic time intervals has
previously been established in short-term studies in which the glycoside was administered …