Several features of cancer cells such as proliferation, invasion, metastatic spreading, and
drug resistance are affected by their interaction with several tumor microenvironment (TME) …

The integration of genomic and DNA methylation data has been demonstrated as a powerful
strategy in understanding cancer mechanisms and identifying therapeutic targets. The TCGA …

Colorectal cancer (CRC) involves epigenetic alterations. Irregular gene-methylation
alteration causes and advances CRC tumor growth. Detecting differentially methylated …

Purpose N6-methyladenosine (m6A) methylation plays a critical role in diverse biological
processes. However, knowledge regarding the constitution of m6A on tumor …

Background SLC10A3, a gene upregulated in pan-cancer, lacks full understanding
regarding its prognostic implications and association with immune infiltration in colorectal …

Introduction: Epigenetic alterations and aberrantly expressed long noncoding RNAs
(lncRNAs) are pervasive in colorectal cancer (CRC) tumorigenesis. DNA methylation could …

Background DNA hypermethylation at promoter CpG islands (CGIs) is a hallmark of cancers
and could lead to dysregulation of gene expression in the development of cancers, however …

Background NOD-like receptor proteins (NLRs) are essential innate pattern recognition
receptors that play fundamental roles in inflammation, and they have been associated with …

As one of crucial epigenetic modification, DNA methylation plays an important role during
the carcinogenesis of colorectal cancer (CRC). In the current study, we used a human …

Tumor cell invasion is one of the key processes during cancer progression, leading to life‐
threatening metastatic lesions in melanoma. As methylation of cancer‐related genes plays a …