Objectives: This study examined whether the administration of intranasal oxytocin was
associated with pain sensitivity, endogenous pain inhibitory capacity, and negative mood …

Background This study examined the effect of synthetic oxytocin delivered intranasally on
acute pain sensitivity using a placebo-controlled, double-blind, within-participant crossover …

Introduction Oxytocin (OXT) is a peptide hormone produced in the hypothalamus that plays a
neuromodulatory role in emotion, stress, and anxiety. Due to its multidimensional role, OXT …

Background Approximately 1.7 million Americans sustain a traumatic brain injury (TBI) each
year and chronic pain is a common complication. Objective We studied the effects of …

Chronic neck and shoulder pain (CNSP) is a common musculoskeletal disorder in adults,
which is linked to hypersensitivity to noxious stimuli. The hormone oxytocin has been …

There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain
and various psychiatric disorders, however, there is scant evidence that oxytocin reaches …

The neuropeptide oxytocin (OT) has been shown to play a modulatory role in nociception.
However, analgesic effects of OT in chronic pain conditions remain elusive and the neural …

Several studies have demonstrated the neuromodulating function of oxytocin (OT) in
response to anxiogenic stimuli as well as its potential role in the pathogenesis of …

Objective Intranasal oxytocin has been shown to affect human social and emotional
processing, but its potential to affect pain remains elusive. This randomized, placebo …

Background There is a need for novel analgesics with favorable risk to benefit profiles.
Oxytocin has recently gained attention for its potential analgesic properties. Aim The aim of …