Studies on the control of antibody synthesis: interaction of antigenic competition and suppression of antibody formation by passive antibody on the immune response

NI Brody, JG Walker, GW Siskind - The Journal of Experimental …, 1967 - rupress.org
In the system studied, antigenic competition between two haptenic determinants was found
to be of the same extent whether the haptens were on the same or on separate carrier …

Studies on the control of antibody synthesis: II. Effect of antigen dose and of suppression by passive antibody on the affinity of antibody synthesized

GW Siskind, P Dunn, JG Walker - The Journal of Experimental …, 1968 - rupress.org
The effect of antigen dose on the kinetics of circulating antibody synthesis and on antibody
affinity was studied in a haptenic system. High doses of antigen resulted, early in …

Studies on the control of antibody synthesis: III. Changes in heterogeneity of antibody affinity during the course of the immune response

TP Werblin, YT Kim, F Quagliata, GW Siskind - Immunology, 1973 - ncbi.nlm.nih.gov
The distribution and heterogeneity of antibody affinity has been followed with time after
immunization. Initially, a symmetrical distribution of heterogeneous low affinity antibody …

Studies on the Control of Antibody Synthesis: V. Effect of Nonspecific Modification of the Magnitude of the Immune Response on the Affinity of the Antibody …

J Mond, YT Kim, GW Siskind - The Journal of Immunology, 1974 - journals.aai.org
A progressive increase in antibody affinity occurred after immunization with
dinitrophenylated keyhole limpet hemocyanin iv in the absence of adjuvants, provided a …

The effect of passively administered antibody on antibody synthesis

FJ Dixon, H Jacot-Guillarmod… - The Journal of …, 1967 - rupress.org
Suppression of the primary response of rabbits to intravenously administered KLH can be
achieved with very small amounts of hyperimmune anti-KLH administered a day later since …

THE INFLUENCE OF ANTIBODIES ON IMMUNOLOGIC RESPONSES: I. THE EFFECT ON THE RESPONSE TO PARTICULATE ANTIGEN IN THE RABBIT

DS Pearlman - The Journal of Experimental Medicine, 1967 - rupress.org
The influence of antibody on antibody formation to particulate antigen was examined in the
rabbit with special reference to the importance of immunoglobulin type, the amount and …

Studies on the regulation of antibody synthesis

H Wigzell - Cold Spring Harbor Symposia on Quantitative …, 1967 - symposium.cshlp.org
Presence of antigen is normally a prerequisite for the induction of detectable antibody
formation (~ terzl, Vesely, Jilek, and Mandel, 1965). After induction of immunity, little is …

REGULATION OF ANTIBODY FORMATION BY SERUM ANTIBODY: II. REMOVAL OF SPECIFIC ANTIBODY BY MEANS OF EXCHANGE TRANSFUSION

JC Bystryn, MW Graf, JW Uhr - The Journal of experimental medicine, 1970 - rupress.org
Rabbits were immunized to two antigens and 18–55 days later exchange transfusion was
performed using blood of rabbits immunized to one antigen only. By this means, serum …

Studies on antigenic competition

NI Brody, GW Siskind - The Journal of experimental medicine, 1969 - rupress.org
Antigenic competition was studied in a haptenic system. It was found that:(a) The extent of
competition is greater when larger doses of antigen are employed.(b) Antigenic competition …

Regulation of Antibody Response in Vitro I. Suppression of Secondary Response by anti-Immunoglobulin Heavy Chains

T Kishimoto, K Ishizaka - The Journal of Immunology, 1971 - journals.aai.org
Abstract Effect of anti-γ chain and anti-µ chain on secondary antibody response of rabbit
spleen cells was studied in vitro. Spleen cells from rabbits primed with dinitrophenylbovine γ …