Exosomes: structure, biogenesis, types and application in diagnosis and gene and drug delivery

S Agarwal, V Agarwal, M Agarwal… - Current Gene …, 2020 - ingentaconnect.com
In recent times, several approaches for targeted gene therapy (GT) had been studied.
However, the emergence of extracellular vesicles (EVs) as a shuttle carrying genetic …

Exosomes: natural nanoparticles as bio shuttles for RNAi delivery

SG Darband, M Mirza-Aghazadeh-Attari… - Journal of Controlled …, 2018 - Elsevier
Application of exosomes, natural nanoscale vesicles, as specific delivery vehicles has
received considerable attention in recent past years. The presence of various adhesive …

Exosomes as nano-theranostic delivery platforms for gene therapy

A Tan, J Rajadas, AM Seifalian - Advanced drug delivery reviews, 2013 - Elsevier
Exosomes are biological membrane vesicles measuring 30 to 100nm. They contain an
abundance of small molecules like tetraspanins, receptors for targeting and adhesion, lipids …

[HTML][HTML] The potential therapeutic value and application prospect of engineered exosomes in human diseases

G Liu, J Wu, G Chen, A Shang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Exosomes are tiny vesicles produced by a wide range of cells that contain complex RNA
and protein. In the diagnosis, treatment, and prevention of illness, they offer great potential …

Exosomes and their application in biomedical field: difficulties and advantages

J Rezaie, S Ajezi, ÇB Avci, M Karimipour… - Molecular …, 2018 - Springer
The science of gene therapy has experienced a controversial history. At first, the initial
concept that various disorders become curable by gene transferring was very exciting and …

Exosomes as novel bio-carriers for gene and drug delivery

XC Jiang, JQ Gao - International journal of pharmaceutics, 2017 - Elsevier
Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …

[HTML][HTML] Expedition into exosome biology: a perspective of progress from discovery to therapeutic development

AT Jan, S Rahman, R Badierah, EJ Lee, EH Mattar… - Cancers, 2021 - mdpi.com
Simple Summary Exosomes symbolize membrane-enclosed entities of endocytic origin.
They play an important role in the intracellular communication by shuttling proteins, nucleic …

The therapeutic applications of exosomes in different types of diseases: a review

M Hosseini, L Roshangar, S Raeisi… - Current molecular …, 2021 - ingentaconnect.com
Exosomes are nano-sized vesicles secreted by nearly all cells and have received massive
attention recently. In addition to their roles in pathophysiological processes and diagnostic …

Exosomes: Biogenesis, targeting, characterization and their potential as" Plug & Play" vaccine platforms

LE Dyball, CM Smales - Biotechnology Journal, 2022 - Wiley Online Library
Exosomes are typically characterized as spherical extracellular vesicles less than 150 nm in
diameter that have been released into the extracellular environment via fusion of …

[HTML][HTML] Biogenesis, biologic function and clinical potential of exosomes in different diseases

A Magdy Beshbishy, S Alghamdi, TGE Onyiche… - Applied Sciences, 2020 - mdpi.com
Exosomes are extracellular vesicles (EVs) belonging to the nanovesicles family that function
as signaling molecules between cells. After their first description in the late 1960s, interest in …