Background Uniparental disomy (UPD) is well-known to be closely intermingled with
imprinting disorders. Besides, UPD can lead to a disease by 'activation'of a recessive gene …

Uniparental disomy (UPD) is often considered as an event to be characterized exclusively
by molecular genetic or epigenetic approaches. This review shows that at least one third of …

Uniparental disomy (UPD) is a topic, which normally is considered to be something
molecular genetics has to take care of exclusively. As UPD is characterized by microsatellite …

Uniparental disomy (UPD) is often the result of an aneuploid event masquerading under the
features of diploidy. As such, it may never be recognized, being at 2 opposite phenotypic …

Objective: To review all cases with segmental and/or complex uniparental disomy (UPD)
and to discuss the impact of these cases on medical genetics. Design: Searching for …

Uniparental disomy (UPD) describes the inheritance of a pair of chromosomes from only one
parent. The concept was introduced in Medical Genetics by Engel (1980); Am J Med Genet …

Uniparental disomy (UPD) is defined as two copies of a whole chromosome derived from the
same parent. There can be multiple mechanisms that lead to UPD; these are reviewed in the …

Uniparental disomy (UPD), the exceptional derivation of a pair of the offspring chromosomes
from one parent only, may be compatible with normal or abnormal development and can …

Uniparental disomy (UPD) is the inheritance of both homologous chromosomes from only
one parent. The bases are always two events, either two meiotic, or one meiotic and one …

Uniparental disomy (UPD) refers to the situation in which both copies of a chromosome pair
have originated from one parent. In humans, it can result in clinical conditions by producing …