Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta

SL Rebholz, KT Burke, Q Yang… - American Journal of …, 2011 - journals.physiology.org
The fetus requires significant energy for growth and development. Although glucose is a
major source of energy for the fetus, other maternal nutrients also appear to promote growth …

[HTML][HTML] The impact of maternal body composition and dietary fat consumption upon placental lipid processing and offspring metabolic health

ZJW Easton, TRH Regnault - Nutrients, 2020 - mdpi.com
The proportion of women of reproductive age who are overweight or obese is increasing
globally. Gestational obesity is strongly associated in both human studies and animal …

[HTML][HTML] Placental lipid processing in response to a maternal high-fat diet and diabetes in rats

EJ Louwagie, TD Larsen, AL Wachal, ML Baack - Pediatric research, 2018 - nature.com
Background Diabetes and obesity during pregnancy have an impact on the health of both
mothers and developing babies. Prevention focuses on glycemic control, but increasing …

Maternal obesity alters placental lysophosphatidylcholines, lipid storage, and the expression of genes associated with lipid metabolism

KL Bidne, AL Rister, AR McCain, BD Hitt… - Biology of …, 2021 - academic.oup.com
Dyslipidemia is a characteristic of maternal obesity and previous studies have demonstrated
abnormalities in fatty acid oxidation and storage in term placentas. However, there is little …

Sex-specific responses in placental fatty acid oxidation, esterification and transfer capacity to maternal obesity

TL Powell, K Barner, L Madi, M Armstrong… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Fatty acid metabolism and oxidation capacity in the placenta, which likely affects the rate
and composition of lipid delivered to the fetus remains poorly understood. Long chain …

Effect of maternal obesity on placental lipid metabolism

V Calabuig-Navarro, M Haghiac, J Minium… - …, 2017 - academic.oup.com
Obese women, on average, give birth to babies with high fat mass. Placental lipid
metabolism alters fetal lipid delivery, potentially moderating neonatal adiposity, yet how it is …

Placental fatty acid transfer

RM Lewis, C Wadsack, G Desoye - Current Opinion in Clinical …, 2018 - journals.lww.com
Placental lipid metabolism is likely to be a determinant of placental transfer of fatty acids to
the fetus. Maternal conditions, such as obesity, have now been shown to regulate placental …

[HTML][HTML] High fat diet administration during specific periods of pregnancy alters maternal fatty acid profiles in the near-term rat

ME Cerf, E Herrera - Nutrients, 2016 - mdpi.com
Excessive fat intake is a global health concern as women of childbearing age increasingly
ingest high fat diets (HFDs). We therefore determined the maternal fatty acid (FA) profiles in …

Placental lipid and fatty acid transfer in maternal overnutrition

RM Lewis, G Desoye - Annals of Nutrition and Metabolism, 2017 - karger.com
Background: The increasing incidence of childhood obesity is a significant public health
challenge, the consequences of which extend across the life course. Summary: Diet and …

Maternal obesity is not associated with placental lipid accumulation in women with high omega-3 fatty acid levels

FL Alvarado, V Calabuig-Navarro, M Haghiac… - Placenta, 2018 - Elsevier
Introduction Placentas of obese women have higher lipid content compared to lean women.
We have previously shown that supplementation of overweight and obese women with …