Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer
MN Skor, EL Wonder, M Kocherginsky, A Goyal… - Clinical Cancer …, 2013 - AACR
Purpose: Triple-negative breast cancer (TNBC) accounts for 10% to 20% of newly
diagnosed invasive breast cancer. Finding effective targets for chemotherapy-resistant …
diagnosed invasive breast cancer. Finding effective targets for chemotherapy-resistant …
Therapeutic strategies for triple-negative breast cancer
AR Tan, SM Swain - The Cancer Journal, 2008 - journals.lww.com
Triple-negative breast cancer (TNBC) is a clinically relevant term referring to breast
carcinomas that do not express the estrogen receptor, progesterone receptor, and human …
carcinomas that do not express the estrogen receptor, progesterone receptor, and human …
Advances in therapeutic approaches for triple-negative breast cancer
R Mahtani, M Kittaneh, K Kalinsky, E Mamounas… - Clinical breast …, 2021 - Elsevier
Triple-negative breast cancer (TNBC), defined as breast cancer lacking expression of
estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 …
estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 …
[HTML][HTML] The role of glucocorticoids in breast cancer therapy
IB Mitre-Aguilar, D Moreno-Mitre, J Melendez-Zajgla… - Current …, 2022 - mdpi.com
Glucocorticoids (GCs) are anti-inflammatory and immunosuppressive steroid molecules
secreted by the adrenal gland and regulated by the hypothalamic–pituitary–adrenal (HPA) …
secreted by the adrenal gland and regulated by the hypothalamic–pituitary–adrenal (HPA) …
[HTML][HTML] 17β-estradiol-induced growth of triple-negative breast cancer cells is prevented by the reduction of GPER expression after treatment with gefitinib
R Girgert, G Emons, C Gründker - Oncology reports, 2017 - spandidos-publications.com
Triple-negative breast cancers (TNBCs) are neither susceptible to endocrine therapy due to
a lack of estrogen receptor α expression nor trastuzumab. TNBCs frequently overexpress …
a lack of estrogen receptor α expression nor trastuzumab. TNBCs frequently overexpress …
[HTML][HTML] Estrogen receptor-beta is a potential target for triple negative breast cancer treatment
D Austin, N Hamilton, Y Elshimali, R Pietras, Y Wu… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Triple Negative breast cancer (TNBC) is a subtype of breast cancer that lacks the expression
of estrogen receptor (ER), progesterone receptor, and human epidermal growth factor …
of estrogen receptor (ER), progesterone receptor, and human epidermal growth factor …
[HTML][HTML] Estrogens and progestogens in triple negative breast cancer: do they harm?
M van Barele, BAM Heemskerk-Gerritsen, YV Louwers… - Cancers, 2021 - mdpi.com
Simple Summary Young women treated for breast cancer may experience early
menopause, which can negatively impact quality of life. The usual treatment for early …
menopause, which can negatively impact quality of life. The usual treatment for early …
[HTML][HTML] Triple-negative breast cancer molecular subtyping and treatment progress
L Yin, JJ Duan, XW Bian, S Yu - Breast Cancer Research, 2020 - Springer
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not
express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth …
express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth …
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
D Horiuchi, L Kusdra, NE Huskey… - Journal of Experimental …, 2012 - rupress.org
Estrogen, progesterone, and HER2 receptor-negative triple-negative breast cancers
encompass the most clinically challenging subtype for which targeted therapeutics are …
encompass the most clinically challenging subtype for which targeted therapeutics are …
Triple negative breast cancer: a brief review of its characteristics and treatment options
CL Griffiths, JL Olin - Journal of pharmacy practice, 2012 - journals.sagepub.com
Triple negative breast cancer (TNBC), an aggressive variant of breast cancer, is
characterized by lack of expression of the estrogen (ER) and progesterone receptors (PRs) …
characterized by lack of expression of the estrogen (ER) and progesterone receptors (PRs) …