The impact of detergents on the tissue decellularization process: a ToF-SIMS study

LJ White, AJ Taylor, DM Faulk, TJ Keane, LT Saldin… - Acta biomaterialia, 2017 - Elsevier
Biologic scaffolds are derived from mammalian tissues, which must be decellularized to
remove cellular antigens that would otherwise incite an adverse immune response …

The surface molecular functionality of decellularized extracellular matrices

CA Barnes, J Brison, R Michel, BN Brown, DG Castner… - Biomaterials, 2011 - Elsevier
Decellularization of tissues and organs is a successful platform technology for creating
scaffolding materials for tissue engineering and regenerative medicine. It has been …

Proteomic analysis of naturally-sourced biological scaffolds

Q Li, BE Uygun, S Geerts, S Ozer, M Scalf, SE Gilpin… - Biomaterials, 2016 - Elsevier
A key challenge to the clinical implementation of decellularized scaffold-based tissue
engineering lies in understanding the process of removing cells and immunogenic material …

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Decellularization systems and devices: State-of-the-art

D Choudhury, M Yee, ZLJ Sheng, A Amirul, MW Naing - Acta biomaterialia, 2020 - Elsevier
Extracellular matrix (ECM) is a natural biomaterial scaffold that provides biochemical and
structural support to its surrounding cells, forming tissue and respective organs. These ECM …

A review of decellularized extracellular matrix biomaterials for regenerative engineering applications

DE Heath - Regenerative Engineering and Translational Medicine, 2019 - Springer
Biomaterials are a cornerstone technology of the biomedical device, tissue engineering, and
regenerative medicine industries. While traditional biomaterials are fully defined synthetics …

A review of decellurization methods caused by an urgent need for quality control of cell‐free extracellular matrix'scaffolds and their role in regenerative medicine

M Kawecki, W Łabuś, A Klama‐Baryla… - … Research Part B …, 2018 - Wiley Online Library
The natural extracellular matrix (ECM), thanks to its specific properties (eg, collagenous
lattice, a reservoir of growth factors, ECM‐cell anchoring areas, an optimal pH and CO2) …

[HTML][HTML] Tissue-specific decellularization methods: rationale and strategies to achieve regenerative compounds

U Mendibil, R Ruiz-Hernandez… - International journal of …, 2020 - mdpi.com
The extracellular matrix (ECM) is a complex network with multiple functions, including
specific functions during tissue regeneration. Precisely, the properties of the ECM have been …

Decellularization of tissues and organs

TW Gilbert, TL Sellaro, SF Badylak - Biomaterials, 2006 - Elsevier
Decellularized tissues and organs have been successfully used in a variety of tissue
engineering/regenerative medicine applications, and the decellularization methods used …

Decellularised scaffolds: just a framework? Current knowledge and future directions

E García-Gareta, Y Abduldaiem… - Journal of Tissue …, 2020 - journals.sagepub.com
The use of decellularised matrices as scaffolds offers the advantage of great similarity with
the tissue to be replaced. Moreover, decellularised tissues and organs can be repopulated …