[HTML][HTML] PGRMC1 regulation by phosphorylation: potential new insights in controlling biological activity!
MA Cahill, JA Jazayeri, Z Kovacevic, DR Richardson - Oncotarget, 2016 - ncbi.nlm.nih.gov
Progesterone receptor membrane component 1 (PGRMC1) is a multifunctional protein
implicated in multiple pathologies, including cancer and Alzheimer's disease. The recently …
implicated in multiple pathologies, including cancer and Alzheimer's disease. The recently …
Progesterone receptor membrane component 1 expression and putative function in bovine oocyte maturation, fertilization, and early embryonic development
AM Luciano, V Lodde, F Franciosi, F Ceciliani… - …, 2010 - rep.bioscientifica.com
Although the mRNA that encodes progesterone receptor membrane component 1
(PGRMC1) is present in mammalian oocytes, nothing is known about either PGRMC1's …
(PGRMC1) is present in mammalian oocytes, nothing is known about either PGRMC1's …
Transmembrane estrogen receptor GPR30 is more frequently expressed in malignant than benign ovarian endometriotic cysts and correlates with MMP-9 expression
L Long, Y Cao, LD Tang - International Journal of Gynecologic Cancer, 2012 - ijgc.bmj.com
Objective Molecular studies supporting the idea of malignant transformation of
endometriosis are sparse and not well substantiated. The aims of this study were to detect …
endometriosis are sparse and not well substantiated. The aims of this study were to detect …
Plasminogen activator inhibitor 1 RNA-binding protein interacts with progesterone receptor membrane component 1 to regulate progesterone's ability to maintain the …
JJ Peluso, A Yuan, X Liu, V Lodde - Biology of reproduction, 2013 - academic.oup.com
Progesterone receptor membrane component 1 (PGRMC1) mediates the antiapoptotic
action of progesterone (P4). PGRMC1 interacts with plasminogen activator inhibitor 1 RNA …
action of progesterone (P4). PGRMC1 interacts with plasminogen activator inhibitor 1 RNA …
GPR30 predicts poor survival for ovarian cancer
HO Smith, H Arias-Pulido, DY Kuo, T Howard… - Gynecologic …, 2009 - Elsevier
OBJECTIVES: GPR30 is a 7-transmembrane G protein-coupled estrogen receptor that
functions alongside traditional estrogen receptors to regulate cellular responses to estrogen …
functions alongside traditional estrogen receptors to regulate cellular responses to estrogen …
E2+ norethisterone promotes the PI3K–AKT pathway via PGRMC1 to induce breast cancer cell proliferation
L Zhang, X Ruan, M Gu, AO Mueck - Climacteric, 2022 - Taylor & Francis
Objective This study aimed to find evidence that progesterone receptor membrane
component 1 (PGRMC1) promotes estradiol (E2)+ norethisterone (NET)-induced breast …
component 1 (PGRMC1) promotes estradiol (E2)+ norethisterone (NET)-induced breast …
Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization
E ZAcHARIAdES, H Foster… - International …, 2011 - spandidos-publications.com
A vital function of the human placenta is to produce steroid hormones such as progesterone,
which are essential for the maintenance of pregnancy and the onset of parturition. Although …
which are essential for the maintenance of pregnancy and the onset of parturition. Although …
Alterations in the expression, structure and function of progesterone receptor membrane component-1 (PGRMC1) in premature ovarian failure
MR Mansouri, J Schuster, J Badhai… - Human molecular …, 2008 - academic.oup.com
Premature ovarian failure (POF) is characterized by hypergonadotropic hypogonadism and
amenorrhea before the age of 40. The condition has a heterogeneous background but …
amenorrhea before the age of 40. The condition has a heterogeneous background but …
[HTML][HTML] Estrogen signaling and its potential as a target for therapy in ovarian cancer
The estrogen receptor (ER) has functionality in selected ovarian cancer subtypes and
represents a potential target for therapy. The majority (> 80%) of high grade serous, low …
represents a potential target for therapy. The majority (> 80%) of high grade serous, low …