PURPOSE: To investigate the protective effects of berberine on radiation-induced lung injury
(RILI) in non-small cell lung cancer (NSCLC) patients treated with radiotherapy. PATIENTS …

PURPOSE: Radiotherapy is the most efficacious strategies for lung cancer. The radiation-
enhancing effects and the underlying mechanisms of berberine were investigated both in …

Berberine, a compound isolated from medicinal herbs, has been reported with many
pharmacological effects related to anti-cancer and anti-inflammation capabilities. In this …

NF-E2-related factor 2 (Nrf2) has been identified as a master regulatory factor in the
protection of cells from oxidative and electrophilic stress. However, overexpression of Nrf2 in …

Radiation therapy is a major treatment in hepatocellular carcinoma (HCC). Yet, this
treatment is ineffective in HCC due to lack of radiosensitivity. For this reason, we examined …

Background Silibinin has been known for its role in anti-cancer and radio-protective effect.
Radiation therapy for treating lung cancer might lead to late-phase pulmonary inflammation …

Nasopharyngeal carcinoma (NPC) is a tumor of epithelial origin with radiotherapy as its
standard treatment. However, radioresistance remains a critical issue in the treatment of …

Conclusion: Berberine confers radiosensitivity on nasopharyngeal carcinoma (NPC) and
this is associated with the down-regulation of hypoxia-inducible factor-1α (HIF-1α) and …

Despite therapeutic advancements, lung cancer remains the principal cause of cancer
mortality in a global scenario. The increased incidence of tumor reoccurrence and …

Berberine, an isoquinoline derivative alkaloid, has recently been shown to have antitumor
activity. The present study aimed to investigate the effects of the concomitant administration …