[HTML][HTML] Berberine hydrochloride inhibits cell proliferation and promotes apoptosis of non-small cell lung cancer via the suppression of the MMP2 and Bcl-2/Bax …

J Li, F Liu, S Jiang, J Liu, X Chen… - Oncology …, 2018 - spandidos-publications.com
Berberine, also known as berberine hydrochloride and isoquinoline alkaloid, is a major
alkaloid from Coptis chinensis. Berberine's extensive biological properties have previously …

[HTML][HTML] Berberine targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and cytochrome-c/caspase signaling to suppress human cancer cell growth

L Fu, W Chen, W Guo, J Wang, Y Tian, D Shi, X Zhang… - PloS one, 2013 - journals.plos.org
Berberine (BBR), an isoquinoline derivative alkaloid isolated from Chinese herbs, has a
long history of uses for the treatment of multiple diseases, including cancers. However, the …

Berberine induces apoptosis in non-small-cell lung cancer cells by upregulating miR-19a targeting tissue factor

Q Chen, J Shi, Z Ding, Q Xia, T Zheng… - Cancer Management …, 2019 - Taylor & Francis
Background Berberine (BBR) from the widely used Chinese herbal medicine Huanglian has
an array of pharmacological and biochemical properties, including anti-neoplastic activity …

Grape seed pro‐anthocyanidins ameliorates radiation‐induced lung injury

Y Huang, W Liu, H Liu, Y Yang, J Cui… - Journal of cellular …, 2014 - Wiley Online Library
Radiation‐induced lung injury (RILI) is a potentially fatal and dose‐limiting complication of
thoracic radiotherapy. This study was to investigate the protective effects of grape seed pro …

Preliminary study of protective effects of flavonoids against radiation-induced lung injury in mice

J Wang, HW Xu, BS Li, J Zhang… - Asian Pacific Journal of …, 2012 - journal.waocp.org
Background: Radiation therapy plays an important role in lung carcinoma treatment.
However, the incidenceof symptomatic radiation-induced lung injury is high. This study …

The anti-cancer mechanisms of berberine: A review

Y Wang, Y Liu, X Du, H Ma, J Yao - Cancer management and …, 2020 - Taylor & Francis
Berberine (BBR) has been extensively studied in vivo and vitro experiments. BBR inhibits
cell proliferation by regulating cell cycle and cell autophagy, and promoting cell apoptosis …

Preventive and therapeutic effects of quercetin on experimental radiation induced lung injury in mice

J Wang, YY Zhang, J Cheng, JL Zhang… - Asian Pacific Journal of …, 2015 - koreascience.kr
Objective: To investigate the protective effect of quercetin on radiation induced lung injury
(RILI) and related mechanisms. Materials and Methods: Mice treated with radiation and/or …

Bisphenol-A/Radiation mediated inflammatory response activates EGFR/KRAS/ERK1/2 signaling pathway leads to lung carcinogenesis incidence

OAR Abo-Zaid, FSM Moawed… - International …, 2022 - journals.sagepub.com
Background Bisphenol (BPA) and ionizing radiation exposure (IR) are potent oxidants that
cause free radical induction, leading to signaling pathway activation that alters cell growth …

In vitro and in vivo antitumor evaluation of berbamine for lung cancer treatment

ZB Hou, KJ Lu, XL Wu, C Chen… - Asian Pacific Journal …, 2014 - koreascience.kr
Purpose: Lung cancer, one of the most frequently diagnosed cancers in the world, is
characterized by relatively high morbidity and mortality. Berbamine (BER) has been initially …

Rosmarinic acid prevents radiation-induced pulmonary fibrosis through attenuation of ROS/MYPT1/TGFβ1 signaling via miR-19b-3p

T Zhang, S Ma, C Liu, K Hu, M Xu… - Dose-Response, 2020 - journals.sagepub.com
The mechanism of pulmonary fibrosis caused by irradiation remains obscure. Since
rosmarinic acid (RA) have anti-oxidant and anti-inflammatory properties, we aimed to …