Abstract# 1398813: A Rare Case of Acromegaly with Negative Immunohistochemical Staining for Growth Hormone

J Rosenwasser, M Candelario-Cosme… - Endocrine …, 2023 - endocrinepractice.org
Discussion Clinical suspicion for acromegaly is confirmed by elevated IGF-1 and GH levels.
When a GH-secreting pituitary adenoma is resected, immunocytochemistry with GH staining …

Clinically silent somatotropinomas may be biochemically active

AA Sakharova, EV Dimaraki… - The Journal of …, 2005 - academic.oup.com
The diagnosis of acromegaly is suspected based on the typical clinical presentation and is
subsequently confirmed biochemically by elevated GH and IGF-I concentrations. We report …

A case of acromegaly without clear evidence of pituitary adenoma or ectopic GH/GHRH secreting tumors

B Fibbi, C Maggioli, L Vannucci, FM De… - Endocrine …, 2012 - endocrine-abstracts.org
Methods: We report the clinical history and the laboratory and imaging results of an
acromegalic woman with no clear evidence of pituitary somatotropinoma or ectopic …

Absence of immunostaining for growth hormone in a subset of patients with acromegaly

JL Schroeder, AM Spiotta, M Fleseriu, RA Prayson… - Pituitary, 2014 - Springer
The presence of growth hormone (GH) immunostaining in patients who lack the biochemical
and clinical features of acromegaly has been described. In contrast, there is little information …

# 1704665 A Giant Tumor Unveiled: A Case Report of A Massive Pituitary Adenoma Inducing Early-onset Acromegaly

CA Balasubramaniapandia… - Endocrine Practice, 2024 - Elsevier
Discussion The young age at presentation makes this case atypical for acromegaly. He had
classic symptoms of acromegaly and found to have markedly elevated IGF-1 levels. The …

Diverse Manifestation of Acromegaly With Suspicion of Ectopic GHRH Secretion. Report of Two Cases

M Godlewska, AJ Nowak, A Boguslawska… - Journal of the …, 2021 - ncbi.nlm.nih.gov
Introduction: Acromegaly can rarely be caused by an ectopic production of GH or GHRH by
various neoplasms, most commonly neuroendocrine tumors of pancreatic or pulmonary …

Endocrinological diagnosis in acromegaly

S Störmann, J Schopohl - Pituitary Tumors, 2021 - Elsevier
Acromegaly is a slowly progressing and rare disease due to excessive growth hormone
(GH) that stems from a pituitary adenoma in most cases. GH is a peptide hormone with …

Acromegaly with normal growth hormone levels: response to Sandostatin-LAR treatment

I Shimon, D Nass, M Hadani - Pituitary, 2000 - Springer
We report a case of acromegaly with relatively low GH secretion in a patient with GH-
secreting pituitary macroadenoma. The 44-year-old male patient presented with left …

Acromegaly in a Young Women With Pituitary Hyperplasia Secondary to a Neuroendocrine Tumor

G Bano - Journal of the Endocrine Society, 2021 - academic.oup.com
Acromegaly is rarely due to an excess of the GH-releasing hormone (GHRH) and pituitary
hyperplasia on histology should alert to its presence. Clinical Case: A 35-year-old was …

Ectopic acromegaly due to a growth hormone-secreting neuroendocrine-differentiated tumor developed from ovarian mature cystic teratoma

M Ozkaya, ZA Sayiner, G Kiran, K Gul, I Erkutlu… - Wiener klinische …, 2015 - Springer
Acromegaly is a clinical syndrome caused by the overproduction of growth hormone (GH)
and also known as a rare disease. Clinical, biochemical, and radiological features are often …