Studies on hydrazone derivatives as antifungal agents

A Özdemir, G Turan-Zitouni… - Journal of Enzyme …, 2008 - Taylor & Francis
The increasing clinical importance of drug-resistant fungal pathogens has urged additional
need to fungal research and new antifungal compound development. For this purpose …

Synthesis and antifungal activity of new hydrazide derivatives

G Turan-Zitouni, MD Altıntop, A Özdemir… - Journal of Enzyme …, 2013 - Taylor & Francis
In this study, nine new hydrazide derivatives were synthesized. The reaction of 2-[(5, 6, 7, 8-
tetrahydronaphthalen-2-yl) oxy] acetohydrazide with various benzaldehydes or …

Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl) thiazol-2-yl) hydrazine derivatives

D Secci, B Bizzarri, A Bolasco, S Carradori… - European journal of …, 2012 - Elsevier
Novel (4-(4-iodophenyl)-thiazol-2-yl) hydrazine derivatives were assayed for their in vitro
anti-Candida activity, compared to topical and systemic antifungal drugs, against twenty …

[HTML][HTML] Synthesis and in vitro evaluation of new nitro-substituted thiazolyl hydrazone derivatives as anticandidal and anticancer agents

MD Altıntop, A Özdemir, G Turan-Zitouni, S Ilgın, Ö Atlı… - Molecules, 2014 - mdpi.com
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their
anticandidal activity using a broth microdilution assay. Among the synthesized compounds …

Synthesis and cytotoxicity of novel (thiazol-2-yl) hydrazine derivatives as promising anti-Candida agents

S Carradori, D Secci, A Bolasco, D Rivanera… - European Journal of …, 2013 - Elsevier
Abstract Thirty-eight new (4-(4-substituted-phenyl/2, 4-disubstituted-phenyl)-thiazol-2-yl)
hydrazine derivatives were synthesized in good yield and assayed for their in vitro anti …

Synthesis and biological evaluation of some hydrazone derivatives as new anticandidal and anticancer agents

MD Altıntop, A Özdemir, G Turan-Zitouni, S Ilgın… - European journal of …, 2012 - Elsevier
New hydrazone derivatives were synthesized via the nucleophilic addition–elimination
reaction of 2-[(1-methyl-1H-tetrazol-5-yl) thio)] acetohydrazide with aromatic …

[PDF][PDF] Synthesis, Characterization and antifungal activity of certain (E)-1-(1-(substitutedphenyl) ethylidene)-2-(6-methylbenzo [d] thiazol-2-yl) hydrazine analogues

G Alang, R Kaur, A Singh, P Budhlakoti, A Singh… - International Journal of …, 2010 - Citeseer
In the present study, five new derivatives (R1 to R5) of benzothiazoles were synthesized and
were evaluated against four fungal strains: Candida albicans (MTCC 183), Aspergillus niger …

[PDF][PDF] 7-Chloroquinolin-4-yl arylhydrazone derivatives: synthesis and antifungal activity

AR Duval, PH Carvalho, MC Soares… - The Scientific …, 2011 - pdfs.semanticscholar.org
Several compounds exhibited minimum inhibitory concentration (MIC) and minimum
fungicidal concentration (MFC) activities comparable with the first-line drug fluconazole …

Synthesis and biological activity of hydrazide–hydrazones and their corresponding 3-acetyl-2, 5-disubstituted-2, 3-dihydro-1, 3, 4-oxadiazoles

B Koçyiğit-Kaymakçıoğlu, EE Oruç-Emre… - Medicinal Chemistry …, 2012 - Springer
Abstract Various 3-acetyl-2, 5-disubstituted-2, 3-dihydro-1, 3, 4-oxadiazoles (11–20) were
prepared by the reaction of aryl substituted hydrazones of 4-fluorobenzoic acid hydrazide (1 …

Synthesis and anticandidal evaluation of new benzothiazole derivatives with hydrazone moiety

L Yurttaş, ZA Kaplancıklı, G Göger… - Journal of Enzyme …, 2016 - Taylor & Francis
In this study, we have performed the synthesis of new N′-(arylidene)-4-[(benzothiazol-2-yl)
thio] butanoylhydrazide derivatives (3a–s) bearing azole moiety and hydrazone group in a …