Background The identification of genes responsible for human inherited diseases is one of
the most challenging tasks in human genetics. Recent studies based on phenotype similarity …

Motivation: Pinpointing genes that underlie human inherited diseases among candidate
genes in susceptibility genetic regions is the primary step towards the understanding of …

High-throughput molecular interaction data have been used effectively to prioritize
candidate genes that are linked to a disease, based on the notion that the products of genes …

Identifying candidate disease genes is important to improve medical care. However, this task
is challenging in the post-genomic era. Several computational approaches have been …

Background Identification of gene-phenotype relationships is a fundamental challenge in
human health clinic. Based on the observation that genes causing the same or similar …

Determining genetic factors underlying various phenotypes is hindered by the involvement
of multiple genes acting cooperatively. Over the past years, disease–gene prioritization has …

With the continuing development and improvement of genome-wide techniques, a great
number of candidate genes are discovered. How to identify the most likely disease genes …

Background High-throughput molecular interaction data have been used effectively to
prioritize candidate genes that are linked to a disease, based on the observation that the …

Genome-wide linkage and association studies have demonstrated promise in identifying
genetic factors that influence health and disease. An important challenge is to narrow down …

The identification of gene–phenotype relationships is very important for the treatment of
human diseases. Studies have shown that genes causing the same or similar phenotypes …