SUMMARY A novel adenosine receptor, the A 3 receptor, has recently been cloned. We
have systematically investigated the hitherto largely unexplored structure-activity …

The A1 adenosine receptor is a member of the seven-transmembrane G protein-coupled,
receptor superfamily. This receptor binds the purine nucleoside adenosine with high affinity …

In this review, Joel linden summarizes what is known about a new and intriguing member of
the adenosine receptor family, the A3 receptor. This receptor exhibits unusually large …

Adenosine receptor (AR) agonists and antagonists are approximately 100-fold and 100,000-
fold, respectively, more potent at the bovine A1AR as compared to the rat A3AR. To …

The amino acids that comprise the ligand binding sites of adenosine receptors have not
been identified. Adenosine and its agonist analogues differ from ligands for the well studied …

A full-length complementary DNA (cDNA) clone encoding the guinea pig brain A 2
adenosine receptor has been isolated by polymerase chain reaction (PCR) and low …

We have characterized the binding of the new potent and selective antagonist radioligand
[3H]‐5‐amino‐7‐(2‐phenylethyl)‐2‐(2‐furyl)‐pyrazolo [4, 3‐e]‐1, 2, 4‐triazolo [1, 5‐c] …

To examine the importance of the nine native cysteine residues in the human A1 adenosine
receptor, each cysteine was individually mutated to both serine and alanine. Saturation …

Sir: Adenosine elicits a wide variety of physiological re-sponses1 via interactions with two
major subtypes of ex-tracellular adenosine receptors, designated as Ax and A2. and A2 …

The rat A 3 adenosine receptor (AR) is a recently characterized AR subtype cloned from
testis and brain cDNA libraries. N 6-2-(4-Amino-3-[125 I] iodophenyl) ethyladenosine, a high …