An interdependent model of central/peripheral chemoreception: evidence and implications for ventilatory control
CA Smith, HV Forster, GM Blain, JA Dempsey - Respiratory physiology & …, 2010 - Elsevier
In this review we discuss the implications for ventilatory control of newer evidence
suggesting that central and peripheral chemoreceptors are not functionally separate but …
suggesting that central and peripheral chemoreceptors are not functionally separate but …
[HTML][HTML] CrossTalk opposing view: Peripheral and central chemoreflexes have additive effects on ventilation in humans
J Duffin, JH Mateika - The Journal of Physiology, 2013 - ncbi.nlm.nih.gov
In humans respiratory chemoreceptors are located centrally in the medulla (Nattie, 2010)
and peripherally in the carotid bodies (Torrance, 1996; Kumar & Bin-Jaliah, 2007). Does the …
and peripherally in the carotid bodies (Torrance, 1996; Kumar & Bin-Jaliah, 2007). Does the …
Contributions of central and peripheral chemoreceptors to the ventilatory response to CO2/H+
HV Forster, CA Smith - Journal of Applied Physiology, 2010 - journals.physiology.org
The major objective of this review is to evaluate existing information and reach conclusions
regarding whether there is interaction between Pco2/H+ stimulation of carotid (peripheral) …
regarding whether there is interaction between Pco2/H+ stimulation of carotid (peripheral) …
Contribution of the carotid body chemoreceptors to eupneic ventilation in the intact, unanesthetized dog
GM Blain, CA Smith, KS Henderson… - Journal of applied …, 2009 - journals.physiology.org
We used extracorporeal perfusion of the reversibly isolated carotid sinus region to determine
the effects of specific carotid body (CB) chemoreceptor inhibition on eupneic ventilation …
the effects of specific carotid body (CB) chemoreceptor inhibition on eupneic ventilation …
Role of chemoreceptors in mediating dyspnea
GF Buchanan, GB Richerson - Respiratory physiology & neurobiology, 2009 - Elsevier
Dyspnea, or the uncomfortable awareness of respiratory distress, is a common symptom
experienced by most people at some point during their lifetime. It is commonly encountered …
experienced by most people at some point during their lifetime. It is commonly encountered …
Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO2
GM Blain, CA Smith, KS Henderson… - The Journal of …, 2010 - Wiley Online Library
We assessed the contribution of carotid body chemoreceptors to the ventilatory response to
specific CNS hypercapnia in eight unanaesthetized, awake dogs. We denervated one …
specific CNS hypercapnia in eight unanaesthetized, awake dogs. We denervated one …
A negative interaction between brainstem and peripheral respiratory chemoreceptors modulates peripheral chemoreflex magnitude
TA Day, RJA Wilson - The Journal of physiology, 2009 - Wiley Online Library
Interaction between central (brainstem) and peripheral (carotid body) respiratory
chemosensitivity is vital to protect blood gases against potentially deleterious fluctuations …
chemosensitivity is vital to protect blood gases against potentially deleterious fluctuations …
The influence of chronic hypoxia upon chemoreception
FL Powell - Respiratory physiology & neurobiology, 2007 - Elsevier
Carotid body chemoreceptors are essential for time-dependent changes in ventilatory
control during chronic hypoxia. Early theories of ventilatory acclimatization to hypoxia …
control during chronic hypoxia. Early theories of ventilatory acclimatization to hypoxia …
Homing in on the specific phenotype (s) of central respiratory chemoreceptors
GB Richerson, W Wang, MR Hodges… - Experimental …, 2005 - Wiley Online Library
To some it may seem that we now know less about respiratory chemoreception than we did
20 years ago. Back then, it was widely accepted that the central respiratory chemoreceptors …
20 years ago. Back then, it was widely accepted that the central respiratory chemoreceptors …
Peripheral chemoreceptors determine the respiratory sensitivity of central chemoreceptors to CO2: role of carotid body CO2
CA Smith, GM Blain, KS Henderson… - The Journal of …, 2015 - Wiley Online Library
Key Points The influence of specific carotid body (CB) normoxic hypocapnia, hypercapnia
and normocapnia on the ventilatory sensitivity of central chemoreceptors to systemic …
and normocapnia on the ventilatory sensitivity of central chemoreceptors to systemic …