White matter hyperintensity volume and impaired mobility among older adults

JZ Willey, N Scarmeas, FA Provenzano… - Journal of …, 2013 - Springer
Gait speed is associated with multiple adverse outcomes of aging. White matter
hyperintensities (WMH) on magnetic resonance imaging (MRI) have been associated with …

Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline

LC Silbert, C Nelson, DB Howieson, MM Moore… - Neurology, 2008 - AAN Enterprises
Background: White matter hyperintensity (WMH) change on brain MRI is observed with
increased frequency in the elderly and has been independently associated with neurologic …

White matter hyperintensities, exercise, and improvement in gait speed: does type of gait rehabilitation matter?

NK Nadkarni, SA Studenski, S Perera… - Journal of the …, 2013 - Wiley Online Library
Objectives To examine whether white matter hyperintensities (WMH s) on brain magnetic
resonance imaging (MRI) in tracts in older adults with mobility impairment are linked to …

Differences in the association between white matter hyperintensities and gait performance among older adults with and without cognitive impairment

R Sakurai, H Inagaki, AM Tokumaru… - Geriatrics & …, 2021 - Wiley Online Library
Aim Gait impairment implies subtle cognitive impairment (CI) and is associated with severity
of white matter hyperintensities (WMHs). However, cognitive differences in such an …

The association between white matter hyperintensity volume and gait performance under single and dual task conditions in older people with dementia: a cross …

R Hairu, JCT Close, SR Lord, K Delbaere… - Archives of Gerontology …, 2021 - Elsevier
Background: Understanding the relationship between white matter hyperintensities (WMHs)
and gait may assist in understanding the central control of gait and determining treatment …

Cerebral white matter and slow gait: contribution of hyperintensities and normal-appearing parenchyma

BL Rosario, AL Rosso, HJ Aizenstein… - The Journals of …, 2016 - academic.oup.com
Background White matter hyperintensities (WMH), a common marker of cerebral small
vessel disease, and lower microstructural integrity of normal-appearing white matter are …

Contributors to poor mobility in older adults: integrating white matter hyperintensities and conditions affecting other systems

AL Rosso, SA Studenski… - … Series A: Biomedical …, 2017 - academic.oup.com
Background Age-related mobility limitations are debilitating and common. Cerebral white
matter hyperintensities (WMH) and conditions affecting other systems are known …

The association between white matter hyperintensity volume and cognitive/physical decline in older people with dementia: A one-year longitudinal study

R Hairu, JCT Close, SR Lord, K Delbaere… - Aging & Mental …, 2022 - Taylor & Francis
Objectives Understanding the relationship between white matter hyperintensities (WMHs)
and cognitive and physical decline in people with dementia will assist in determining …

Progression of white matter hyperintensities of presumed vascular origin increases the risk of falls in older people

ML Callisaya, R Beare, T Phan… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Greater volume of cerebral white matter hyperintensities (WMH) of presumed
vascular origin may affect postural control and gait. WMH measured at one time point …

Impact of regional white matter hyperintensities on specific gait function in Alzheimer's disease and mild cognitive impairment

N Ogama, H Endo, S Satake, S Niida… - Journal of cachexia …, 2021 - Wiley Online Library
Background Gait disturbance and musculoskeletal changes are evident in persons living
with Alzheimer's disease (AD). Because complex gait control requires the integration of …