Depression of natural killer cytotoxicity after in vivo administration of recombinant leukocyte interferon.
AE Maluish, JR Ortaldo, JC Conlon… - … (Baltimore, Md.: 1950 …, 1983 - journals.aai.org
One hundred thirty-four patients with a variety of malignancies were treated in two phase I
clinical trials of recombinant leukocyte A interferon (IFL-rA) produced by recombinant DNA …
clinical trials of recombinant leukocyte A interferon (IFL-rA) produced by recombinant DNA …
Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and …
G Trinchieri, D Santoli - The Journal of experimental medicine, 1978 - rupress.org
Interferon, induced in lymphocytes either with viruses or cell lines, increases severalfold the
natural cytotoxicity of human lymphocytes on target cell lines. Cell separation experiments …
natural cytotoxicity of human lymphocytes on target cell lines. Cell separation experiments …
[PDF][PDF] Analysis by a single cell cytotoxicity assay of natural killer (NK) cells frequencies among human large granular lymphocytes and of the effects of interferon on …
T Timonen, JR Ortaldo… - Journal of immunology …, 1982 - scholar.archive.org
MATERIALS AND METHODS Culture conditions. All target cells were cultured, and
experiments were carried out at 37 C in a humidified air atmosphere with 5% Con. using …
experiments were carried out at 37 C in a humidified air atmosphere with 5% Con. using …
Abnormal natural killer cytotoxicity in primary biliary cirrhosis: evidence for a functional deficiency of cytolytic effector cells
SP James, EA Jones - Gastroenterology, 1985 - Elsevier
The in vitro cytotoxic activity of peripheral blood lymphocytes from patients with primary
biliary cirrhosis was investigated to determine the mechanism of deficient spontaneous cell …
biliary cirrhosis was investigated to determine the mechanism of deficient spontaneous cell …
Enhancement by interferon of natural killer cell activity in mice
A Senik, I Gresser, C Maury, M Gidlund, A Orn… - Cellular …, 1979 - Elsevier
Injection of mice with several interferon inducers, Newcastle Disease virus, polyinosinic-
polycytidylic acid and tilorone resulted in an increase in spleen cell cytotoxicity for 51 …
polycytidylic acid and tilorone resulted in an increase in spleen cell cytotoxicity for 51 …
Natural killer cells in carcinomatous pleural effusions
A Uchida, M Micksche - Cancer Immunology, Immunotherapy, 1981 - Springer
Effector cells in carcinomatous pleural effusions of patients with primary or secondary lung
cancer were examined for natural killer (NK) activity against K562 cells in a 4-h chromium …
cancer were examined for natural killer (NK) activity against K562 cells in a 4-h chromium …
Induction of NK cell activity against fresh human leukemia in culture with interleukin 2.
E Lotzova, CA Savary, RB Herberman - Journal of immunology …, 1987 - journals.aai.org
Natural killer (NK) cells have been implicated in defense against malignancies, especially
leukemia. Because patients with leukemia and preleukemic disorders manifest low NK …
leukemia. Because patients with leukemia and preleukemic disorders manifest low NK …
Natural killer cells in human solid tumors
M Introna, A Mantovani - Cancer and Metastasis Reviews, 1983 - Springer
Natural killer (NK) cells have been studied in human neoplastic diseases in an effort to
assess the role of these cells in the control of human neoplasia and to monitor the effects of …
assess the role of these cells in the control of human neoplasia and to monitor the effects of …
Natural killer cells in children with malignant solid tumors. Effect of recombinant interferon‐α and interleukin‐2 on natural killer cell function against tumor cell lines
CS Alvarado, HW Findley, WC Chan, RS Hnath… - Cancer, 1989 - Wiley Online Library
Natural killer (NK) cells and NK cell activity were determined in three groups (newly
diagnosed [n= 21], on therapy [n= 21], and off therapy [n= 18]) of children with various types …
diagnosed [n= 21], on therapy [n= 21], and off therapy [n= 18]) of children with various types …
Human tumour—lymphocyte interaction in vitro. V. Comparison of the reactivity of tumour‐infiltrating, blood and lymph‐node lymphocytes with autologous tumour …
BM Vose, F Vanky, E Klein - International journal of cancer, 1977 - Wiley Online Library
Lymphocytes prepared from the blood, tumour‐draining lymph node and tumour were tested
for immune reactivity with freshly isolated autologous tumour cells from biopsies. Reactivity …
for immune reactivity with freshly isolated autologous tumour cells from biopsies. Reactivity …