Fresh neoplastic B cells from 14 untreated patients with naturally occurring B‐cell leukemias
were found to be susceptible to lysis by human natural killer (NK) cells. The observed lysis of …

The capacity of interferon (IFN) given once or repeatedly to augment natural killer (NK) cell
activity in the spleen was tested in young and aged C57BL/6 mice. Multiple injections of 104 …

Patients with advanced cancer exhibited lower natural cytotoxicity against K562 target cells
in a standard short-term chromium release assay than did patients with localized …

Requirement for macrophages in in vitro augmentation, by interferon (IFN), polyinosinic-
polycytidylic acid (poly I: C), or Corynebacterium parvum, of rat, mouse, and human natural …

The in vitro cytotoxic activity of two types of hepatic sinusoidal cells, ie, natural killer (NK)
cells and macrophages (Kupffer cells), was tested against a syngeneic rat colon …

The host defense mechanism against tumor can be classified into two major immune
systems, adaptive immunity and natural immunity. Adaptive immunity is acquired and …

The purpose of this study was to determine (1) the number and activity of natural killer (NK)
cells in children with acute leukemia at different stages of their disease; and (2) the effect of …

The ability of NK cells to lyse noncultured solid tumor cells was investigated, and the results
were compared with lysis of K562. Purified NK cell fractions separated by either Percoll …

Publisher Summary This chapter examines the association of human natural killer (NK) cell
activity against human primary tumors with large granular lymphocytes (LGL). It discusses …