Vasopressin is a 9-amino acid peptide synthesized by magnocellular neurons of the
hypothalamus and released from posterior pituitary gland. The primary physiological role of …

Exogenous vasopressin is a promising vasopressor when blood pressure is critically
threatened, but the role of endogenous vasopressin during cardiopulmonary resuscitation …

Background The current guidelines for cardiopulmonary resuscitation recommend
vasopressin as an alternative to epinephrine for the treatment of adult shock-refractory …

Arginine vasopressin (AVP), a hormone secreted by the posterior pituitary, plays a vital role
in maintaining vasomotor tone during acute blood loss. We hypothesized that …

OBJECTIVES We sought to determine the effects of vasopressin and saline placebo in
comparison with epinephrine on neurologic recovery and possible cerebral pathology in an …

Survival after hypovolemic shock and cardiac arrest is dismal with current therapies. We
evaluated the potential benefits of vasopressin versus large-dose epinephrine in …

Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

Historically, epinephrine has been used in the treatment of cardiac arrest for its alpha effects
of peripheral vasoconstriction to promote vital organ perfusion. Unfortunately, epinephrine …

Background: Vasopressin is essential for cardiovascular homeostasis, acting via the kidney
to regulate water resorption, on the vasculature to regulate smooth muscle tone, and as a …

Management of the potential organ donor in critical care units is the most immediate and
practical solution to the current crisis in organ donation. Brain death physiology significantly …