The in vitro stability and in vivo pharmacokinetics of curcumin prepared as an aqueous nanoparticulate formulation

C Mohanty, SK Sahoo - Biomaterials, 2010 - Elsevier
Curcumin, the natural anticancer drug and its optimum potential is limited due to lack of
solubility in aqueous solvent, degradation at alkaline pH and poor tissue absorption. In order …

Design and In Vitro Evaluation of a New Nano‐Microparticulate System for Enhanced Aqueous‐Phase Solubility of Curcumin

D Guzman-Villanueva, IM El-Sherbiny… - BioMed research …, 2013 - Wiley Online Library
Curcumin, a yellow polyphenol derived from the turmeric Curcuma longa, has been
associated with a diverse therapeutic potential including anti‐inflammatory, antioxidant …

Recent advances in curcumin nanoformulation for cancer therapy

WH Lee, CY Loo, PM Young, D Traini… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Natural compounds are emerging as effective agents for the treatment of
malignant diseases. Curcumin (diferuloylmethane), the active constituent of turmeric extract …

[HTML][HTML] Novel delivery system for natural products: Nano-curcumin formulations

HR Rahimi, R Nedaeinia, AS Shamloo… - Avicenna journal of …, 2016 - ncbi.nlm.nih.gov
Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal
pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis …

Progress in nanotechnology-based drug carrier in designing of curcumin nanomedicines for cancer therapy: current state-of-the-art

MZ Ahmad, SA Alkahtani, S Akhter… - Journal of drug …, 2016 - Taylor & Francis
Comprehensive pharmacological screening of curcumin (CUR) has given the evidence that
it is an excellent naturally occurring therapeutic moiety for cancer. It is very well tolerated …

Purely aqueous PLGA nanoparticulate formulations of curcumin exhibit enhanced anticancer activity with dependence on the combination of the carrier

KL Nair, AKT Thulasidasan, G Deepa, RJ Anto… - International journal of …, 2012 - Elsevier
Curcumin, a yellow pigment present in turmeric, possess potential anti-proliferative and anti-
inflammatory activities but poor aqueous solubility limits its applications. In this study we …

Curcumin nanoformulations: a future nanomedicine for cancer

MM Yallapu, M Jaggi, SC Chauhan - Drug discovery today, 2012 - Elsevier
Curcumin, a natural diphenolic compound derived from turmeric Curcuma longa, has proven
to be a modulator of intracellular signaling pathways that control cancer cell growth …

Preparation, characterization, in vitro drug release and biological studies of curcumin loaded dextran sulphate–chitosan nanoparticles

A Anitha, VG Deepagan, VVD Rani, D Menon… - Carbohydrate …, 2011 - Elsevier
Nanoformulation of curcumin,(a low molecular weight hydrophobic drug) was prepared by
using dextran sulphate and chitosan. The developed nanoparticles were characterized by …

Herbal approach for treatment of cancer using curcumin as an anticancer agent: A review on novel drug delivery systems

U Hani, BHJ Gowda, A Siddiqua, S Wahab… - Journal of Molecular …, 2023 - Elsevier
The polyphenol compound curcumin originates from the rhizomes of Curcuma longa Linn.
The anti-cancer effects of curcumin and its analogues are described in extensive detail and …

Particle size effect of curcumin nanosuspensions on cytotoxicity, cellular internalization, in vivo pharmacokinetics and biodistribution

C Bi, XQ Miao, SF Chow, WJ Wu, R Yan… - … , Biology and Medicine, 2017 - Elsevier
This study aimed to investigate the particle size effect on bioactivity, cellular internalization
and bioavailability of curcumin (CUR) nanosuspension (CUR-NS). CUR-NSs of different …