Background: Sickle cell disease (SCD) is a monogenetic disorder resulting from a point
mutation in β-globin gene leading to synthesis of abnormal hemoglobin S. SCD patients are …

BACKGROUND AND OBJECTIVES: Sickle cell disease (SCD) is a chronic, inherited
haemoglobin disorder, associated with recurrent vaso-occlusive and haemolytic crises and …

Background: Cardiac dysfunctions have been recognized as a common complication of
sickle cell anaemia (SCA), and together with pulmonary disorder accounts for many deaths …

Introduction: Sickle cell disease (SCD) is chronic, inherited haemoglobin disorder,
associated with chronic tissue ischemia which may adversely affect any organ system …

BACKGROUND AND OBJECTIVES: Sickle cell disease is an important chronic inherited
haemoglobin disorder, associated with recurrent vaso-occlusive and haemolytic crises and …

Background. Abnormal lipid homeostasis in sickle cell disease (SCD) is characterized by
defects in plasma and erythrocyte lipids and may increase the risk of cardiovascular …

Background: Sickle cell disease (SCD) is an autosomal recessive blood disorder
characterized by abnormal hemoglobin formation, leading to a more rigid and sickle-shaped …

Background: Cardiovascular abnormalities are important causes of morbidity and mortality
in sickle cell disease (SCD) patients. Data on electrocardiography (ECG) changes in SCD …

Abstract Background: Pulse Doppler echocardiography has a diagnostic value in right and
left ventricular function in patients with homozygous sickle cell disease (SCD), however the …

Purpose: Sickle cell disease (SCD) is one of the known autosomal recessive hereditary
disorders of hemoglobin known to associate with serious complications and responsible for …