Cardiovascular roles of tachykinin peptides in the nucleus tractus solitarii of rats

A Nagashima, Y Takano, K Tateishi, Y Matsuoka… - Brain research, 1989 - Elsevier
Unilateral removal of the afferent fibers of the IXth and Xth cranial nerve (nodose
ganglionectomy) caused significant decrease in the content of substance P-like …

Ablation of NK1 receptors in rat nucleus tractus solitarii blocks baroreflexes

J Riley, LH Lin, DA Chianca Jr, WT Talman - Hypertension, 2002 - Am Heart Assoc
The neuropeptide substance P (SP) is found in vagal afferent nerves within the nucleus
tractus solitarii, where it is released on stimulation of arterial baroreflexes. The neurokinin-1 …

Colocalization of neurokinin-1, N-methyl-D-aspartate, and AMPA receptors on neurons of the rat nucleus tractus solitarii

LH Lin, OM Taktakishvili, WT Talman - Neuroscience, 2008 - Elsevier
Substance P (SP) and glutamate are implicated in cardiovascular regulation by the nucleus
tractus solitarii (NTS). Our earlier studies suggest that SP, which acts at neurokinin 1 (NK1) …

Central pressor actions of neurokinin B: increases in neurokinin B contents in discrete nuclei in spontaneously hypertensive rats

A Nagashima, Y Takano, K Tateishi, Y Matsuoka… - Brain research, 1989 - Elsevier
The regional distributions of neurokinin B-like immunoreactivity and substance P-like
immunoreactivity in the central nervous system in spontaneously hypertensive rats (SHRs) …

Ablation of NK1 receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats

APL Abdala, GHM Schoorlemmer, E Colombari - Brain research, 2006 - Elsevier
The nucleus of the solitary tract (NTS) receives primary afferents involved in cardiovascular
regulation. We investigated the role of NK1-receptor bearing neurons in the NTS on …

Neurokinin1 receptor mediation of the vasodepressor effects of substance P in the nucleus of the tractus solitarius.

PD Feldman - Journal of Pharmacology and Experimental …, 1995 - ASPET
The involvement of substance P (SP) in cardiovascular regulatory mechanisms was
investigated in the nucleus of the tractus solitarius (nTS) of urethane-anesthetized Wistar …

Cardiovascular effects produced by bradykinin microinjection into the nucleus tractus solitarii of anesthetized rats

SM Caligiorne, RAS Santos, MJ Campagnole-Santos - Brain research, 1996 - Elsevier
In this study, we characterized the cardiovascular effects produced by microinjection of
doses in the femtomole range of bradykinin (BK) into the nucleus tractus solitarii of male …

Characterization of the tachykinin receptors involved in spinal and supraspinal cardiovascular regulation

R Couture, P Picard, P Poulat… - Canadian journal of …, 1995 - cdnsciencepub.com
The pharmacological characterization of the tachykinin receptors involved in spinal and
supraspinal cardiovascular regulation is reviewed in this report. In conscious rats, substance …

Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress

J Culman, S Klee, C Ohlendorf, T Unger - Journal of Pharmacology and …, 1997 - ASPET
The neurokinins, substance P (SP) and neurokinin A (NKA) represent natural, nonspecific
ligands of NK1 and NK2receptors. In our study in conscious rats, we tested the hypothesis …

Neurokinin release in the rat nucleus of the solitary tract via NMDA and AMPA receptors

I Colin, C Blondeau, A Baude - Neuroscience, 2002 - Elsevier
Neurokinins (substance P, neurokinin A and neurokinin B) and the neurokinin receptors, the
NK1 and NK3 receptors, are largely expressed in the nucleus of the solitary tract (NST) …