Microcirculatory alterations play a pivotal role in sepsis-related morbidity and mortality.
However, since the microcirculation has been a “black box”, current hemodynamic …

Microcirculation plays an important role in the pathogenesis of shock and organ dysfunction,
especially in sepsis. Monitoring microcirculation at the bedside may be used to assess …

The microcirculation describes the smallest elements of the cardiovascular conducting
system and is pivotal in the maintenance of homeostasis. Microcirculatory dysfunction is …

Microcirculatory dysfunction has been recently recognized as a key pathophysiologic
process in the evolution of sepsis. In the present review, we discuss fundamental aspects of …

Microcirculation alterations are present in shock states, mainly septic shock, and can have a
prognostic role and be the target of therapeutic interventions. To date, microcirculation …

Abnormal microvascular perfusion, including decreased functional capillary density and
increased blood flow heterogeneity, is observed in early stages of the systemic inflammatory …

Largely ignored throughout the history of clinical medicine, the microcirculation has recently
been recognized at the bedside as the center of several pathophysiological processes …

The microcirculation is altered in sepsis, and the degree and persistence of these alterations
are associated with outcome. When there are significant alterations of the systemic …

Purpose: Clinically unapparent microcirculatory impairment is common and has a negative
impact on septic shock, but specific therapy is not established so far. This prospective …

Sepsis is a leading cause of mortality in critically ill patients. The pathophysiology of sepsis
involves a highly complex and integrated response, including the activation of various cell …