OBJECTIVE AND METHODS: The knowledge of the mechanisms underlying the adhesive
processes that lead to homing and/or mobilization of hematopoietic progenitor cells, and the …

Molecular mechanisms leading to mobilization of hematopoietic cells from bone marrow
(BM) to peripheral blood (PB) involve modulation of adhesion molecule expression on these …

The role of leukocyte-endothelial cell interactions during granulocyte colony-stimulating
factor (G-CSF)-induced stem cell mobilization is unclear. To examine endothelial activation …

We have evaluated the immunophenotype, functional activity and clonogenic potential of
CD34+ cells from peripheral blood (PB) of normal donors before and after 4 and 6 days of G …

The mechanisms responsible for mobilization of hematopoietic progenitor cells (HPC) from
the bone marrow into the circulation are unknown. One possibility is that HPC downregulate …

Cellular interactions between hematopoietic progenitor cells and bone marrow (BM) stromal
cells are mediated by cell adhesion molecules (CAM). In agreement with previous studies …

To determine the effect of growth factor mobilization on the expression of adhesion
molecules, we compared CD34+ progenitor cell (PC) populations from steady-state bone …

The purpose of this study is to investigate the function of the main adhesion receptors on
CD34+ cells during hematopoietic stem cell transplantation. Expression was quantified by …

Background Cell adhesion molecules (CAMs) expressed on hematopoietic progenitor cells
(HPCs), endothelial cells, and stromal cells play a pivotal role in the mobilization of CD34+ …

The β2 integrins leukocyte function antigen-1 (LFA-1, CD11a) and macrophage antigen-1
(Mac-1, CD11b) have been reported to play a role in the attachment of CD34+ cells to …