[PDF][PDF] Molecular strategies of meiotic cheating by selfish centromeres
Asymmetric division in female meiosis creates selective pressure favoring selfish
centromeres that bias their transmission to the egg. This centromere drive can explain the …
centromeres that bias their transmission to the egg. This centromere drive can explain the …
[PDF][PDF] Parallel pathways for recruiting effector proteins determine centromere drive and suppression
T Kumon, J Ma, RB Akins, D Stefanik, CE Nordgren… - Cell, 2021 - cell.com
Selfish centromere DNA sequences bias their transmission to the egg in female meiosis.
Evolutionary theory suggests that centromere proteins evolve to suppress costs of this" …
Evolutionary theory suggests that centromere proteins evolve to suppress costs of this" …
Centromere drive: model systems and experimental progress
D Dudka, MA Lampson - Chromosome Research, 2022 - Springer
Centromeres connect chromosomes and spindle microtubules to ensure faithful
chromosome segregation. Paradoxically, despite this conserved function, centromeric DNA …
chromosome segregation. Paradoxically, despite this conserved function, centromeric DNA …
Cellular and molecular mechanisms of centromere drive
MA Lampson, BE Black - Cold Spring Harbor symposia on …, 2017 - symposium.cshlp.org
The asymmetric outcome of female meiosis I, whereby an entire set of chromosomes are
discarded into a polar body, presents an opportunity for selfish genetic elements to cheat the …
discarded into a polar body, presents an opportunity for selfish genetic elements to cheat the …
Spindle asymmetry drives non-Mendelian chromosome segregation
Genetic elements compete for transmission through meiosis, when haploid gametes are
created from a diploid parent. Selfish elements can enhance their transmission through a …
created from a diploid parent. Selfish elements can enhance their transmission through a …
[PDF][PDF] Expanded satellite repeats amplify a discrete CENP-A nucleosome assembly site on chromosomes that drive in female meiosis
A Iwata-Otsubo, JM Dawicki-McKenna, T Akera… - Current Biology, 2017 - cell.com
Female meiosis provides an opportunity for selfish genetic elements to violate Mendel's law
of segregation by increasing the chance of segregating to the egg [1]. Centromeres and …
of segregation by increasing the chance of segregating to the egg [1]. Centromeres and …
Conflict begets complexity: the evolution of centromeres
HS Malik, S Henikoff - Current opinion in genetics & development, 2002 - Elsevier
Centromeres mediate the faithful segregation of eukaryotic chromosomes. Yet they display a
remarkable range in size and complexity across eukaryotes, from∼ 125 bp in budding yeast …
remarkable range in size and complexity across eukaryotes, from∼ 125 bp in budding yeast …
Duplication and Adaptive Evolution of a Key Centromeric Protein in Mimulus, a Genus with Female Meiotic Drive
FR Finseth, Y Dong, A Saunders… - Molecular biology and …, 2015 - academic.oup.com
The fundamental asymmetry of female meiosis creates an arena for genetic elements to
compete for inclusion in the egg, promoting the selfish evolution of centromere variants that …
compete for inclusion in the egg, promoting the selfish evolution of centromere variants that …
The cellular mechanisms and consequences of centromere drive
Highlights•Cortical CDC42 signaling leads to asymmetric tyrosination of meiosis I spindle
microtubules.•Centromeric DNA expansion recruits more CenH3, increases centromere …
microtubules.•Centromeric DNA expansion recruits more CenH3, increases centromere …
Centromeres: selfish drivers
S Henikoff, HS Malik - Nature, 2002 - nature.com
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