The mammalian tachykinins (substance P, neurokinin A, and neurokinin B) are widely
distributed throughout the central and peripheral nervous systems, where they act as …

The structurally related neuropeptides, substance P (SP), neurokinin A (NKA), and
neurokinin B (NKB), which belong to a family of molecules termed tachykinins and are …

The tachykinins, substance P, neurokinin A and neurokinin B, are a family of neuropeptides
widely distributed in the mammalian central and peripheral nervous system. In the …

The involvement of tachykinin neuropeptides, such as substance P and the neurokinins, in
pain transmission is supported by a wealth of evidence. At present. the therapeutic potential …

This review addresses the recent highlights and progress made in the neurokinin-3 (NK-3)
receptor area since the last update, provided in this journal in 1997. Whereas in the …

Publisher Summary This chapter focuses on the progress in the development of neurokinin
(NK) antagonists. The neurokinins substance P (SP), neurokinin A (NKA), and neurokinin B …

Tachykinins are a family of peptides that share the common C-terminal sequence, Phe-X-Gly-
Leu-Met-NH,. In mammals, at least three different tachykinins, namely, substance P (SP) …

A number of extensive reviews have been published which cover much of the current
literature on receptor distribution, in vitro and in vivo pharmacology, potential clinical utilities …

Publisher Summary The neurokinins, a class of peptide neurotransmitters, characterized by
the common C-terminal sequence Phe-X-Gly-Leu Met-NH 2, are widely distributed in the …

A family of peptides that shares a common C-terminal sequence (Phe-X-Gly-Leu-MetNH 2)
exists in mammalian and non-mammalian species. In mammals, three of these peptides …